Table 1

Demographics, spirometry, respiratory muscle strength and ventilator pressure settings of the study population

Diagnosis
All participants (n=24)Restrictive chest wall disease (n=4)Neuromuscular disease (n=7)Obstructive lung disease (n=3)Obesity hypoventilation syndrome (n=10)
Age (years)56(24)35.5 (8)60 (47)74 (30)58 (11)
Male (n)141418
BMI (kg/m2)33.3 (25.4)21 (3.1)31.9 (8.05)38.6 (22.6)52.6 (11.7)
FEV1 (L)1.3 (0.68)0.61 (0.13)1.6 (0.38)1.3 (0.79)1.53 (0.92)
FEV1 (%)50 (24.5)29 (3.5)55 (15)52 (35.5)51 (24.3)
FVC (L)1.9 (0.88)0.73 (0.04)1.9 (0.37)2.2 (0.6)2.4 (1.58)
FVC (%)62 (23.5)29 (8.5)62 (15.5)72 (18.5)59 (19.5)
FEV1/FVC73(18)88 (15.5)78 (10.5)55 (25)69 (18.25)
MIP (mm Hg)43 (13)40 (7)42.5 (8.5)31*52 (31)
MIP (%)49 (28)63 (15.5)47 (15.25)31*54 (17)
MEP (mm Hg)94 (68)80 (31.5)44 (22.5)82*119 (25.5)
MEP (%)73(49)88 (40.5)36.5 (22.75)81*83 (11.5)
EPAP (cmH2O)10.5 (8)8.5 (2.25)8 (5)10 (8)16 (2.75)
PS (cmH2O)8 (4)10 (0.75)8 (1.5)12 (09)7 (3.75)
  • Data presented are count or median (IQR).

  • *MIP and MEP values only attained from one participant with obstructive lung disease.

  • BMI, body mass index; EPAP, expiratory positive airway pressure; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; IPAP, inspiratory positive airway pressure; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; PS, pressure support.