Association between pulmonary diagnosis and Kexin (KEX1) RET
| Cohort | Severe asthma | Mild and moderate asthma | Non-asthma | Cystic fibrosis |
| All patients | n=51 | n=20 | n=20 | n=13 |
| Primary outcome | ||||
| High KEX1 RET | 8 | 9 | 8 | 10 |
| Low KEX1 RET | 43 | 11 | 12 | 3 |
| OR of low KEX1 RET in patients with severe asthma | ||||
| Value | – | 4.40 | 3.58 | 17.92 |
| 95% CI, Baptista-Pike | – | 1.28 to 13.25 | 1.20 to 10.84 | 4.15 to 66.62 |
| Association between pulmonary diagnosis and binary KEX1 RET indicator | ||||
| Fisher’s exact test p value | – | 0.014* | 0.055 | <0.0001*** |
*P<0.05, ***p<0.001.
KEX1, Kexin; OR, Odds Ratio; RET, reciprocal end point titre.