Table 2

Pulmonary function test results at the time of initial clinic visit according to type of interstitial lung disease

FVC (% predicted)TLC (% predicted)DLco (% predicted)
IPF mean (SD)79.2 (19.1)78.0 (16.5)57.7 (17.1)
Non-IPF mean (SD)82.6 (19.2)82.6 (18.4)59.6 (19.3)
CTD-related77.3 (20.1)76.10 (18.3)55.4 (18.1.0)
HP85.7 (13.3)85.1 (14.4)64.2 (19.3)
Unclassifiable ILD78.6 (15.8)77.5 (19.3)47.0 (14.7)
Non-specific PF99.4 (19.6)94.6 (13.9)70.4 (19.6)
NSIP77.9 (23.9)81.2 (21.0)56.4 (15.6)
Drug related82.9 (17.8)82.3 (21.7)56.4 (18.6)
Smoking-related ILD97.0 (17.4)96.0 (19.8)47.7 (16.8)
Other83.0 (15.9)89.7 (14.2)80.9 (15.9)
  • There was no significant difference in FVC (p=0.13), TLC (p=0.03), or DLco (p=0.39) between IPF and non-IPF ILD patients, as the p value required to achieve statistical significance is <0.01 after applying Bonferroni’s correction for multiple comparisons.

  • CTD, connective tissue disease; DLco, carbon monoxide diffusing capacity; n=269; FVC, forced vital capacity; n=287; IPF, idiopathic pulmonary fibrosis; PF, pulmonary fibrosis; TLC, total lung capacity; n=284.