Pulmonary function test results at the time of initial clinic visit according to type of interstitial lung disease
FVC (% predicted) | TLC (% predicted) | DLco (% predicted) | |
IPF mean (SD) | 79.2 (19.1) | 78.0 (16.5) | 57.7 (17.1) |
Non-IPF mean (SD) | 82.6 (19.2) | 82.6 (18.4) | 59.6 (19.3) |
CTD-related | 77.3 (20.1) | 76.10 (18.3) | 55.4 (18.1.0) |
HP | 85.7 (13.3) | 85.1 (14.4) | 64.2 (19.3) |
Unclassifiable ILD | 78.6 (15.8) | 77.5 (19.3) | 47.0 (14.7) |
Non-specific PF | 99.4 (19.6) | 94.6 (13.9) | 70.4 (19.6) |
NSIP | 77.9 (23.9) | 81.2 (21.0) | 56.4 (15.6) |
Drug related | 82.9 (17.8) | 82.3 (21.7) | 56.4 (18.6) |
Smoking-related ILD | 97.0 (17.4) | 96.0 (19.8) | 47.7 (16.8) |
Other | 83.0 (15.9) | 89.7 (14.2) | 80.9 (15.9) |
There was no significant difference in FVC (p=0.13), TLC (p=0.03), or DLco (p=0.39) between IPF and non-IPF ILD patients, as the p value required to achieve statistical significance is <0.01 after applying Bonferroni’s correction for multiple comparisons.
CTD, connective tissue disease; DLco, carbon monoxide diffusing capacity; n=269; FVC, forced vital capacity; n=287; IPF, idiopathic pulmonary fibrosis; PF, pulmonary fibrosis; TLC, total lung capacity; n=284.