Table 1

Patients’ baseline characteristics

CharacteristicsOverall (N=136)Arm
CCP+SOC (n=69)SOC (n=67)
Age, median (IQR)50 (38.5–62)48 (35–64)53 (44–61)
Sex, male, n (%)97 (71.3)48 (69.6)49 (73.1)
At least one symptom123 (90.4)61 (88.4)62 (92.5)
Fever45 (33.1)22 (31.9)23 (34.4)
Sore throat10 (7.4)7 (10.1)3 (4.5)
Cough85 (62.5)38 (55.1)47 (70.2)
Difficulty with breathing70 (51.5)37 (53.6)33 (49.3)
Chest pain57 (41.9)29 (42.0)28 (41.8)
Loss of taste12 (8.8)8 (11.6)4 (6.0)
Rhinorrhoea2 (1.5)1 (1.5)1 (1.5)
Others18 (13.2)8 (11.6)10 (14.9)
Symptom length, M (IQR)7 (4–8)7 (3–7)7 (5–10)
Temperature ≥37.5°C, n (%)1 (0.7)0 (0.0)1 (1.5)
SPO2 <93%, n (%)38 (27.9)19 (27.5)19 (28.4)
Pulse rate ≥100, n (%)45 (33.1)20 (29.0)25 (37.3)
BP ≥130/90, n (%)40 (29.4)20 (29.0)20 (29.9)
BMI >30, n/N (%)15/45 (33.3)8/24 (33.3)7/21 (33.3)
At least one comorbidity79 (58.1)39 (56.5)40 (59.7)
Hypertension49 (36.0)24 (34.8)25 (37.3)
Diabetes mellitus32 (23.5)17 (24.6)15 (22.4)
Asthma5 (3.7)5 (7.3)0 (0.0)
Tuberculosis4 (2.9)1 (1.5)3 (4.5)
HIV15 (11.0)4 (5.8)11 (16.4)
Others16 (11.8)9 (13.0)7 (10.5)
Medications, n (%)
 Corticosteroids80 (58.8)36 (52.2)44 (65.7)
 Anticoagulant80 (58.8)35 (50.7)45 (67.2)
 Oxygen therapy66 (48.5)28 (40.6)38 (56.7)
 Oxygen 1–5 L/min35 (53.0)13 (46.4)22 (57.9)
 Oxygen >5 L/min31 (47.0)15 (53.6)16 (42.1)
 Non-invasive ventilation1 (0.7)1 (1.5)0 (0.0)
 WCC ≥10 x 109/L, n=369 (25)4 (20.)5 (31.3)
 WCC ≤4000/mm35 (13.9)3 (15)2 (12.5)
 Neutrophil ≤1500/mm32 (5.6)2 (10)0 (0)
 Lymphocyte ≤1500/mm321 (58.3)13(65)8 (50)
 Platelets <150 000/ mm36 (16.7)5 (25)1 (6.3)
 Haemoglobin ≤1 g/L000
 AST >40 U/L, n/n=113 (%)37 (32.7)14 (25.0)23 (40.4)
 ALT >40 U/L, n/N (%)7 (6.2)5 (8.9)2 (3.5)
 Creatinine ≥1.2 g/dL, n/N (%)20 (17.7)11 (19.5)9 (15.8)
 Bilirubin total >1.2 mg/dL (%)77 (68.1)40 (71.4)37 (64.9)
 CRP ≥10 mg/L, n/N (%)81 (71.7)39 (69.5)42 (73.7)
 CXR score, median (SD), n=348.9 (6.4)7.4 (7.3)10.2 (5.3)
  • ALT, alanine transferase; AST, aspartate transferase; BMI, body mass index; BP, blood pressure; CCP, convalescent plasma; CRP, C reactive protein; CXR, chest X-ray; SOC, standard of care; SPO2, oxygen saturation; WCC, white cell count.