Analysis in never smokers: HRs for fatal (death on day 1) and non-fatal coronary events per 1-SD decrease in lung function measures (n=9947)
| Fatal coronary events (SCD) (n=364) | Non-fatal coronary events (n=1064) | P value* | ||
| FEV1 | Model 1 | 1.44 (1.24 to 1.66) | 1.17 (1.07 to 1.27) | 0.0162 |
| Model 2 | 1.34 (1.15 to 1.55) | 1.11 (1.02 to 1.21) | 0.0380 | |
| FVC | Model 1 | 1.48 (1.26 to 1.72) | 1.22 (1.11 to 1.33) | 0.0369 |
| Model 2 | 1.36 (1.16 to 1.59) | 1.16 (1.05 to 1.27) | 0.0880 | |
| FEV1/FVC | Model 1 | 1.01 (0.92 to 1.13) | 0.99 (0.93 to 1.05) | 0.6462 |
| Model 2 | 1.02 (0.92 to 1.12) | 0.98 (0.93 to 1.05) | 0.6160 |
Model 1: age, sex, height.
Model 2: age, sex, height, BMI, prevalent diabetes, systolic BP, cholesterol.
*Null hypothesis: lung function measure has the same association with incident fatal coronary events and incident non-fatal coronary events.
BMI, body mass index; BP, blood pressure; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; SCD, sudden cardiac death.