Proportion of SARS-CoV-2 due to lineage B.1.1.7 for all inpatient sequenced samples according to patient characteristics
| Lineage B.1.1.7 (n=1107) | Not lineage B.1.1.7 (n=1234) | Total (n=2341) | |
| Age group (years) | |||
| 0–11 | 15 (62.5) | 9 (37.5) | 24 (100) |
| 12–24 | 20 (58.8) | 14 (41.2) | 34 (100) |
| 25–34 | 61 (62.9) | 36 (37.1) | 97 (100) |
| 35–49 | 159 (56.2) | 124 (43.8) | 283 (100) |
| 50–69 | 371 (53.2) | 326 (46.8) | 697 (100) |
| 70–79 | 208 (42.2) | 285 (57.8) | 493 (100) |
| 80+ | 273 (38.3) | 440 (61.7) | 713 (100) |
| Sex | |||
| Female | 534 (46.1) | 624 (53.9) | 1158 (100) |
| Male | 573 (48.4) | 610 (51.6) | 1183 (100) |
| Sample week starting | |||
| 16 November 2020 | 15 (8.4) | 164 (91.6) | 179 (100) |
| 23 November 2020 | 26 (11.6) | 198 (88.4) | 224 (100) |
| 30 November 2020 | 59 (24.2) | 185 (75.8) | 244 (100) |
| 07 December 2020 | 55 (26.8) | 150 (73.2) | 205 (100) |
| 14 December 2020 | 138 (43.8) | 177 (56.2) | 315 (100) |
| 21 December 2020 | 220 (54.6) | 183 (45.4) | 403 (100) |
| 28 December 2020 | 361 (75.2) | 119 (24.8) | 480 (100) |
| 04 January 2021 | 233 (80.1) | 58 (19.9) | 291 (100) |
| Patient class | |||
| HCW | 7 (36.8) | 12 (63.2) | 19 (100) |
| CAI* | 847 (55.1) | 689 (44.9) | 1536 (100) |
| Indeterminate HCAI† | 54 (25.4) | 159 (74.6) | 213 (100) |
| Probable/definite HCAI‡ | 199 (34.7) | 374 (65.3) | 573 (100) |
| Region | |||
| Glasgow | 91 (31.6) | 197 (68.4) | 288 (100) |
| Hampshire | 74 (60.2) | 49 (39.8) | 123 (100) |
| London | 871 (65.7) | 455 (34.3) | 1326 (100) |
| South Yorkshire | 71 (11.8) | 533 (88.2) | 604 (100) |
| Ethnicity | |||
| White | 540 (39.4) | 829 (60.6) | 1369 (100) |
| Black | 174 (53.4) | 152 (46.6) | 326 (100) |
| Asian | 118 (63.1) | 69 (36.9) | 187 (100) |
| Mixed or other | 186 (67.1) | 91 (32.9) | 277 (100) |
| Unknown | 89 (48.9) | 93 (51.1) | 182 (100) |
| Patient characteristics | |||
| Obese (BMI ≥35) | 122 (51) (N=1107) | 117 (49) (N=1234) | 239 (100) (N=2341) |
| Pregnant | 25 (55.6) (N=1103) | 20 (44.4) (N=1234) | 45 (100) (N=2337) |
| Care home resident | 45 (36.3) (N=1107) | 79 (63.7) (N=1232) | 124 (100) (N=2339) |
| Comorbidities | |||
| None | 337 (56.6) | 258 (43.4) | 595 (100) |
| One | 307 (47.3) | 342 (52.7) | 649 (100) |
| Two | 261 (45.9) | 308 (54.1) | 569 (100) |
| Three or more | 202 (38.4) | 324 (61.6) | 526 (100) |
| Not recorded | 0 (0) | 2 (100) | 2 (100) |
| Died within 28 days | 217 (41.2) (N=1106) | 310 (58.8) (N=1230) | 527 (100) (N=2336) |
| Admitted to ITU within 28 days§ | 220 (65.3) (N=1081) | 117 (34.7) (N=1214) | 337 (100) (N=2295) |
Data shown as n (%), with (N) with available data shown where missing values possible.
*Diagnosed at or ≤2 days from admission.
†Diagnosed 3–7 days from admission.
‡Diagnosed ≥8 days from admission.
§Excluding patients admitted to ITU prior to SARS-CoV-2 diagnosis.
BMI, body mass index; CAI, community-acquired infection; HCAI, healthcare-associated infection; HCW, healthcare worker; ITU, intensive therapy unit.