Baseline (year 1) demographic and clinical characteristics of patients before and after COPD diagnosis
| Variables | Prior to COPD diagnosis (n=11 482) | After COPD diagnosis (n=1778) | Total (n=13 260) |
| Age, mean (SD), years | 69 (10) | 70 (9) | 69 (10) |
| Sex, male, no. (%) | 6526 (57) | 1029 (58) | 7555 (57) |
| Body mass index, mean (SD), kg/m2 | 27 (6) | 27 (6) | 27 (6) |
| Body mass index, no. (%) with data | 11 409 (99) | 1759 (99) | 13 168 (99) |
| Underweight | 403 (3) | 85 (5) | 488 (4) |
| Normal weight | 4066 (36) | 643 (37) | 4709 (36) |
| Overweight | 4070 (36) | 588 (33) | 4658 (35) |
| Obese | 2870 (25) | 443 (25) | 3313 (25) |
| Smoking status, no. (%) | |||
| Active smoker | 4467 (39) | 648 (36) | 5115 (39) |
| Former smoker | 7015 (61) | 1130 (64) | 8145 (61) |
| COPD severity, no. (%) with data | 5859 (51) | 925 (52) | 6784 (51) |
| Mild | 1957 (33) | 293 (32) | 2250 (33) |
| Moderate | 2831 (48) | 433 (47) | 3264 (48) |
| Severe | 975 (17) | 177 (19) | 1152 (17) |
| Very severe | 96 (2) | 22 (2) | 118 (2) |
| COPD exacerbations in the past year, mean (SD) | 0.3 (0.9) | 0.5 (1.3) | 0.3 (1.0) |
| COPD exacerbations in the past year, no. (%) | |||
| 0 | 9736 (85) | 1395 (79) | 11 131 (84) |
| 1 | 998 (8) | 195 (11) | 1193 (9) |
| 2 | 433 (4) | 79 (4) | 512 (4) |
| >2 | 315 (3) | 109 (6) | 424 (3) |
| Forced expiratory volume in 1 s, mean (SD), L | 0.7 (0.2) | 0.7 (0.2) | 0.7 (0.2) |
| Emphysema, no. (%) | 646 (6) | 248 (14) | 894 (7) |
| Diabetes, no. (%) | 1771 (15) | 280 (16) | 2051 (16) |
| Hypertension, no. (%) | 5317 (46) | 823 (46) | 6140 (46) |
| Coronary artery disease, no. (%) | 675 (6) | 106 (6) | 781 (6) |
| Acute myocardial infarction, no. (%) | 822 (7.) | 144 (8) | 966 (7) |
| Congestive cardiac failure, no. (%) | 719 (6) | 110 (6) | 829 (6) |
| Anxiety, no. (%) | 938 (8) | 142 (8) | 1080 (8) |
| Depression, no. (%) | 3490 (30) | 582 (33) | 4072 (31) |
| Treatment, no. (%) | |||
| ICS | 5082 (44) | 1056 (59) | 6138 (46) |
| ICS+LABA | 4486 (39) | 969 (55) | 5455 (41) |
| LAMA | 5363 (47) | 985 (55) | 6348 (48) |
| LABA | 1101 (10) | 147 (8) | 1248 (9) |
| SAMA | 581 (5) | 100 (6) | 681 (5) |
| Mucolytics | 1028 (9) | 231 (13) | 1259 (10) |
COPD, chronic obstructive pulmonary disease; ICS, inhaled corticosteroids; LABA, long-acting beta agonist; LAMA, long-acting antimuscarinic; SAMA, short-acting antimuscarinic.