Proposed markers of the disease
| Concept | Measures |
| Lung function | Normalised spirometry measure, bronchoprovocation measures, reversibility |
| Atopy | Immune trajectory, aeroallergen/food through in-vivo or in-vitro testing |
| Atopy symptoms | Presence, frequency and severity of allergic rhinoconjunctivitis, atopic dermatitis, allergic rhinitis, food allergy |
| Respiratory symptoms | Presence, frequency and severity of wheeze, cough, episodic shortness of breath |