Survival modelling in fHP
| Covariate | Univariate analysis | Multivariate analysis | ||||
| HR (95% CI) | P value | N | HR (95% CI) | P value | N | |
| Age | 1.05 (1.03 to 1.08) | <0.0001 | 251 | 1.04 (1.01 to 1.08) | 0.0091 | 156 |
| Gender | 0.73 (0.30 to 1.17) | 0.1591 | 279 | 0.79 (0.14 to 1.45) | 0.4851 | 156 |
| Stratified monocytes | 1.45 (0.67 to 2.24) | 0.3508 | 226 | 0.85 (–0.15 to 1.85) | 0.7519 | 156 |
| Stratified NLR | 1.44 (0.89 to 1.99) | 0.2584 | 225 | 1.46 (0.76 to 2.17) | 0.2878 | 156 |
| FVC % predicted | 0.98 (0.97 to 1.00) | 0.0107 | 198 | 0.99 (0.95 to 1.02) | 0.4272 | 156 |
| FEV1 % predicted | 0.99 (0.98 to 1.00) | 0.086 | 198 | 1.01 (0.97 to 1.04) | 0.6428 | 156 |
| TLCO % predicted | 0.97 (0.95 to 0.99) | 0.0014 | 162 | 0.97 (0.94 to 1.00) | 0.0358 | 156 |
In multivariate analysis, younger age and higher baseline TLCO showed better survival rates.
%, percentage; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; n, number; NLR, neutrophil to lymphocyte ratio; P value, statistical significance; TLCO, transfer factor for carbon monoxide.