Evaluable children, n† | ppFEV1, mean (SD), percentage points | |
Overall | 4481 | 92.6 (17.5) |
F508del/F508del | 2251 | 92.2 (17.5) |
F508del/MF | 968 | 92.1 (17.5) |
Gating mutation on ≥1 allele | 218 | 95.0 (16.6) |
RF on ≥1 allele | 170 | 98.3 (16.4) |
MF/MF | 163 | 87.4 (19.1) |
R117H on ≥1 allele | 96 | 97.9 (11.8) |
*ppFEV1 is not routinely measured in children <6 years of age.
†n indicates the number of children with non-missing data.
MF, minimal function; ppFEV1, per cent predicted forced expiratory volume in 1 s; RF, residual function.