Observational data
| Observational data | ECCO2R group (n=26) | Control group (n=25) | P value |
| Duration between NIV and ECCO2R or IMV (hours) | 42±69 | 20±35 | 0.15 |
| Days on ECCO2R | 5,4±4 | N/A | |
| Days on IMV | N/A | 27±43 | |
| Curarisation | N/A | 7 (28) | |
| Prone position or NO | N/A | 0 | |
| IMV rate | 4 (15) | N/A | |
| Tracheotomy | 2 (8) | 5 (20) | 0.38 |
| NIV during ECCO2R | 18 (69) | N/A | |
| HFNOT during ECCO2R | 7 (27) | N/A | |
| Haemodynamic instability* | 3 (12) | 16 (64) | 0.0001 |
| RRT | 3 (12) | 3 (12) | 1 |
| HIT | 0 | 1 (4) | 0.98 |
| Pulmonary embolism | 2 (8) | 1 (4) | 1 |
| Weaning from successful ECCO2R or IMV | 17 (65) | 16 (64) | 0.91 |
Values are presented as mean±SD or number (%).
*With catecholamine administration required.
ECCO2R, extracorporeal CO2 removal; HFNOT, high flow nasal oxygen therapy; HIT, heparin-induced thrombocytopenia; ICU, intensive care unit; IMV, invasive mechanical ventilation; N/A, not applicable; NIV, non-invasive ventilation; NO, nitrogen monoxide; RRT, renal replacement therapy.