Baseline patient characteristics
| Patient characteristics | ECCO2R group (n=26) | Control group (n=25) | P value |
| Demographic data | |||
| Gender (male) | 20 (77) | 17 (68) | 0.48 |
| Age (years) | 67±12 | 72±11 | 0.08 |
| BMI (kg/m²) | 30±9 | 25±7 | 0.035 |
| SAPS II | 49±14 | 50±15 | 0.81 |
| Glasgow | 13±3 | 12,4±3,6 | 0.62 |
| Comorbidities | |||
| Hypertension | 13 (50) | 16 (64) | 0.31 |
| Diabetes | 8 (31) | 10 (40) | 0.49 |
| Renal failure | 4 (15) | 1 (4) | 0.37 |
| Heart failure | 6 (23) | 7 (28) | 0.69 |
| Coronary heart disease | 6 (23) | 6 (24) | 0.94 |
| Atrial fibrillation | 3 (12) | 6 (24) | 0.42 |
| Stroke | 2 (8) | 2 (8) | 1 |
| Sleep apnoea | 5 (19) | 2 (8) | 0.45 |
| Asthma | 1 (4) | 2 (8) | 0.97 |
| Cancer <5 years | 2 (8) | 6 (24) | 0.22 |
| Systemic corticosteroid | 1 (4) | 3 (12) | 0.57 |
| LTOT | 11 (42) | 10 (40) | 0.87 |
| NIV | 7 (27) | 4 (16) | 0.34 |
| Causes of exacerbation | |||
| Influenza A | 4 (15) | 0 | 0.13 |
| Bronchitis | 15 (58) | 9 (36) | 0.34 |
| Heart failure | 9 (35) | 6 (24) | 0.41 |
| None identified | 4 (15) | 10 (40) | 0.09 |
| Arterial blood gases 6 hours before | |||
| pH | 7,24±0,05 | 7,23±0,13 | 0.91 |
| PaCO2 (mm Hg) | 86±21 | 82±24 | 0.64 |
| PaO2 (mm Hg) | 69±28 | 78±31 | 0.43 |
| Bicarbonates (mmol/L) | 36±9 | 37±9 | 0.75 |
Values are presented as mean±SD or number (%).
BMI, body mass index; ECCO2R, extracorporeal carbon dioxide removal; LTOT, long-term oxygen therapy; N/A, not applicable; NIV, non-invasive ventilation; SAPS II, Simplified Acute Physiology Score II.