Multifactorial determinants of changes in D-12 questionnaire scores
| Baseline | Estimates±SE | P value |
| ΔM2-baseline D-12 physical | ||
| BMI,1 kg/m2 increase | −0.12±0.04 | 0.003 |
| ΔM2-baseline D-12 affective | ||
| FEV1, 1% of predicted value increase | −0.06±0.02 | 0.001 |
| Anxiety symptom, score >11 | 1.83±0.61 | 0.003 |
| 6MST, 1 stroke increase | −0.005±0.002 | 0.007 |
| ΔM2-baseline D-12 total score | ||
| FEV1, 1% of predicted value increase | −0.06±0.02 | <0.001 |
| 6MST, 1 stroke increase | −0.004±0.002 | 0.048 |
Results from the backward stepwise multivariable ANCOVA. A significance level of 0.20 in parametric analysis (table 3) was used to keep the most important explanatory relationship variables in the final model. Multiple imputations were used and data were adjusted for baseline value.
ANCOVA, analysis of covariance; BMI, body mass index; D-12, Dyspnoea-12; FEV1, forced expiratory volume in 1 s; 6MST, 6 min stepper test.