Concordance of EGFR testing results from NGS, MassArray and qPCR
| Mutations | Variants | NGS vs MassArray | NGS vs qPCR | MassArray vs qPCR |
| EGFR sensitising mutations | Exon 18 p.G719A | 100% (23/23) | 100% (12/12) | 100% (12/12) |
| Exon 20 p.S768I | 100% (23/23) | 100% (12/12) | 100% (12/12) | |
| Exon 21 p.L858R | 95.7% (22/23) | 100% (12/12) | 91.7% (11/12) | |
| Exon 21 p.L861Q | 100% (23/23) | 100% (12/12) | 100% (12/12) | |
| Exon 19 deletions | 95.7% (22/23) | 91.7% (11/12) | 91.7% (11/12) | |
| TKIs resistant EGFR mutation | Exon 20 p.T790M | 91.3% (21/23) | 91.7% (11/12) | 100% (12/12) |
EGFR, epidermal growth factor receptor; NGS, next-generation sequencing; TKI, tyrosine kinase inhibitor.