Changes in L-PF Dyspnoea and Cough scores across strata of 52-week change in global physical health score
| Change in L-PF global physical health score† | F-statistic‡ | Pairwise comparisons§ | ||||||||||
| Large deterioration | Minimal/Moderate deterioration | Stable | Minimal/Moderate improvement | Large improvement | ||||||||
| N | Mean (SD) change from baseline | N | Mean (SD) change from baseline | N | Mean (SD) change from baseline | N | Mean (SD) change from baseline | N | Mean (SD) change from baseline | |||
| L-PF Dyspnoea score | 6 | 17.6 (28.8) | 159 | 8.7 (16.8) | 244 | 5.7 (14.5) | 120 | 0.6 (15.6) | 8 | 1.0 (8.6) | 5.7*** | 6** |
| L-PF Cough score | 5 | 5.8 (27.7) | 157 | 4.8 (24.8) | 242 | 1.5 (23.3) | 121 | −5.9 (23.8) | 8 | 0.0 (22.6) | 3.6** | 6** |
L-PF Symptoms scores range from 0 to 100, with higher scores indicating greater impairment.
**p<0.01, ***p<0.001.
†Question 20: on average, over the last 7 days, how have you felt in terms of physical health? Scale: 0 (extremely poor) to 4 (excellent). Large deterioration: change of −3 or −4; minimal/moderate deterioration: change of −2 or −1; stable: change of 0; minimal/moderate improvement: change of +1 or +2; large improvement: change of +3 or +4.
‡One-way analyses of variance (generalised linear model) overall F-statistic.
§Pairwise comparisons using Scheffe’s method: 1=large deterioration versus minimal/moderate deterioration, 2=large deterioration versus stable, 3=large deterioration versus minimal/moderate improvement, 4=large deterioration versus large improvement, 5=minimal/moderate deterioration versus stable, 6=minimal/moderate deterioration versus minimal/moderate improvement, 7=minimal/moderate deterioration versus large improvement, 8=stable versus minimal/moderate improvement, 9=stable versus large improvement, 10=minimal/moderate improvement versus large improvement.
L-PF, Living with Pulmonary Fibrosis.