Table 2

Clinical description of respondents including self-reported activities reduced/ceased by mMRC (n=828)

mMRCP value
0 (n=573)1 (n=107)2 (n=69)3 (n=43)4 (n=36)
Hospital anxiety and depression scale (HADS)*AnxietyNormal (0–7)505 (91.7)86 (81.9)54 (79.4)31 (72.1)20 (64.5)<0.001
Borderline (8–10)33 (6.0)10 (9.5)7 (10.3)5 (11.6)3 (9.7)
Abnormal (11–21)13 (2.4)9 (8.6)7 (10.3)7 (16.3)8 (25.8)
DepressionNormal (0–7)529 (95.5)91 (86.7)58 (84.1)32 (80.0)21 (61.8)<0.001
Borderline (8–10)17 (3.1)9 (8.6)9 (13.0)5 (12.5)9 (26.5)
Abnormal (11–21)8 (1.4)5 (4.8)2 (2.9)3 (7.5)4 (11.8)
Body mass index (BMI) (WHO categories)Underweight/healthy weight196 (35.1)22 (21.4)14 (20.6)5 (11.6)4 (11.4)<0.001
Overweight297 (53.2)56 (54.4)29 (42.7)23 (53.5)10 (28.6)
Obese65 (11.7)25 (24.3)25 (36.8)15 (34.9)21 (60.0)
WHO Performance StatusFully active; no performance restrictions.474 (83.8)66 (62.3)29 (42.0)11 (26.2)8 (23.5)<0.001
Strenuous physical activity restricted; fully ambulatory and able to carry out light work.74 (13.1)35 (33.1)34 (49.3)22 (52.4)16 (47.1)
More limited than capable of all self-care but unable to carry out any work activities. Up and about >50% of waking hours.18 (3.2)5 (4.7)6 (8.7)9 (21.4)10 (29.4)
Self-rated exertion
n (%)
Sedentary21 (3.7)11 (10.59 (13.4)12 (27.9)9 (25.7)<0.001
Moderate exercise329 (58.7)71 (67.6)47 (70.2)24 (55.8)22 (62.9)
Moderate but regular exercise173 (30.8)23 (21.9)8 (11.9)6 (14.0)3 (8.6)
Frequent exercise38 (6.8)0 (0)3 (4.5)1 (2.3)1 (2.9)
Additional therapies/supportsUse walking aids; n (%)6 (1.1)0 (0)1 (1.5)5 (13.9)1 (3.2)<0.001
Use oxygen therapy; n (%)3 (0.6)1 (1.0)2 (3.1)1 (2.7)4 (12.5)<0.001
Activities reduced/ceasedPhysical activities19 (3.3)27 (25.5)23 (33.3)21 (48.8)27 (75.0)<0.001
Social contacts12 (2.1)7 (6.6)4 (5.8)11 (25.6)12 (33.3)<0.001
Associations18 (3.1)11 (10.4)5 (7.4)12 (27.9)12 (34.3)<0.001
Talking on the phone8 (1.4)8 (7.6)2 (2.9)7 (16.3)6 (16.7)<0.001
Sexual activities37 (6.5)24 (22.8)17 (25.0)22 (51.2)22 (61.1)<0.001
Other5 (0.9)2 (2.5)6 (12.5)0 (0)3 (20.0)<0.001
  • *Respondents’ numbers reflect complete data for that measure.

  • mMRC, modified Medical Research Council.