Factors associated with LTBI treatment initiation among contacts diagnosed with LTBI from 2009 to 2018, Brunei (n=982 out of 1047 (93.8%))
| LTBI treatment initiated (n=430) n (%) | LTBI treatment not initiated (n=552) n (%) | Crude OR | 95% CI | Adjusted OR | 95% CI | ||
| Contact factors | |||||||
| Age group (years) | 0–5 | 7 (1.6) | 26 (4.7) | 0.29 | 0.07 to 1.17 | 0.17 | 0.04 to 0.81 |
| 5–14 | 21 (4.9) | 59 (10.7) | 0.30 | 0.09 to 1.02 | 0.22 | 0.05 to 0.87 | |
| 15–29 | 141 (32.8) | 164 (29.7) | 0.76 | 0.24 to 2.48 | 0.67 | 0.18 to 2.54 | |
| 30–44 | 140 (32.5) | 183 (33.2) | 0.64 | 0.20 to 2.06 | 0.58 | 0.15 to 2.19 | |
| 45–59 | 96 (22.3) | 98 (17.8) | 0.81 | 0.25 to 2.68 | 0.77 | 0.20 to 3.00 | |
| 60–74 | 17 (4.0) | 19 (3.4) | 0.74 | 0.20 to 2.75 | 0.49 | 0.11 to 2.15 | |
| 75+ | 8 (1.9) | 3 (0.5) | 1 | 1 | |||
| Gender | Male | 254 (59.1) | 328 (59.4) | 1.08 | 0.84 to 1.40 | 1.18 | 0.90 to 1.54 |
| Female | 176 (40.9) | 224 (40.6) | 1 | 1 | |||
| Nationality | Local | 361 (84.0) | 415 (75.2) | 1.57 | 1.11 to 2.23 | 1.86 | 1.26 to 2.73 |
| Foreign | 69 (16.0) | 137 (24.8) | 1 | 1 | |||
| District of residence | Brunei-Muara | 107 (24.9) | 112 (20.3) | 1 | 1 | ||
| Belait | 176 (40.9) | 228 (41.3) | 0.80 | 0.53 to 1.20 | 0.83 | 0.54 to 1.28 | |
| Tutong | 142 (33.0) | 185 (33.5) | 0.75 | 0.49 to 1.15 | 0.72 | 0.46 to 1.13 | |
| Temburong | 5 (1.2) | 27 (4.9) | 0.25 | 0.09 to 0.73 | 0.20 | 0.07 to 0.61 | |
| Type of contact | Household | 235 (54.7) | 286 (51.8) | 1.05 | 0.72 to 1.54 | 1.15 | 0.74 to 1.79 |
| Workplace | 159 (37.0) | 207 (37.5) | 1 | 1 | |||
| School | 31 (7.2) | 33 (6.0) | 1.13 | 0.40 to 3.26 | 1.23 | 0.43 to 3.54 | |
| Others | 5 (1.1) | 26 (4.7) | 0.44 | 0.14 to 1.41 | 0.38 | 0.11 to 1.26 | |
| Index factors | |||||||
| Age group (years) | 0–14 | 9 (2.1) | 7 (1.3) | 0.93 | 0.16 to 5.32 | 1.07 | 0.21 to 5.43 |
| 15–29 | 98 (22.8) | 127 (23.0) | 0.82 | 0.45 to 1.46 | 0.89 | 0.48 to 1.65 | |
| 30–44 | 131 (30.5) | 172 (31.1) | 0.85 | 0.48 to 1.52 | 1.02 | 0.56 to 1.86 | |
| 45–59 | 110 (25.5) | 170 (30.8) | 0.72 | 0.40 to 1.29 | 0.72 | 0.39 to 1.34 | |
| 60–74 | 48 (11.2) | 39 (7.1) | 1.10 | 0.55 to 2.18 | 1.46 | 0.72 to 2.94 | |
| 75+ | 34 (7.9) | 37 (6.7) | 1 | 1 | |||
| Gender | Male | 304 (70.7) | 410 (74.3) | 0.91 | 0.64 to 1.31 | 0.99 | 0.67 to 1.47 |
| Female | 126 (29.3) | 142 (25.7) | 1 | 1 | |||
| Type of PTB | Smear positive | 334 (77.6) | 426 (77.2) | 1.15 | 0.71 to 1.85 | ||
| Smear negative | 48 (11.2) | 72 (13.0) | 1 | ||||
| Other | 48 (11.2) | 54 (9.8) | 1.18 | 0.61 to 2.25 | |||
| Nationality | Local | 362 (84.2) | 438 (79.3) | 1.36 | 0.89 to 2.06 | ||
| Foreign | 68 (15.8) | 114 (20.7) | 1 | ||||
| Year of diagnosis | 2009–13 | 198 (46.0) | 323 (58.5) | 1 | 1 | ||
| 2014–18 | 232 (54.0) | 229 (41.5) | 1.43 | 1.03 to 1.99 | 1.39 | 0.98 to 1.98 | |
Bold values indicate statistically significant results
LTBI, latent TB infection; PTB, pulmonary TB.