Cumulative incidence of community-acquired pneumonia and acute otitis media before and after implementation of 13-valent pneumococcal conjugate vaccine (PCV13) programme stratified by age group in Ontario and British Columbia, 2005–2018
| Age group | Incidence per 100 000 population (95% CI) | |||
| Community-acquired pneumonia | Acute otitis media | |||
| Pre-PCV13 period | PCV13 period | Pre-PCV13 period | PCV13 period | |
| Ontario | ||||
| 0–4 years | 4854.2 (4515.7 to 5218.2) | 4991.1 (4801.0 to 5188.7) | 28 937.9 (27 623.6 to 30 314.8) | 25 467.6 (24 766.2 to 26 188.9) |
| 5–17 years | 1289.8 (1189.1 to 1399.1) | 1249.0 (1192.4 to 1308.4) | 7998.6 (7598.8 to 8419.5) | 7225.9 (7002.8 to 7456.1) |
| 18–39 years | 855.5 (795.3 to 920.2) | 815.9 (783.6 to 849.5) | 2491.7 (2330.0 to 2664.7) | 2204.4 (2118.2 to 2294.2) |
| 40–64 years | 1465.8 (1391.7 to 1543.8) | 1529.9 (1488.9 to 1572.1) | 2245.5 (2102.5 to 2398.2) | 2058.6 (1981.7 to 2138.5) |
| 65–74 years | 3167.5 (2928.7 to 3425.7) | 3095.7 (2979.6 to 3216.3) | 2093.7 (1799.7 to 2435.9) | 1954.7 (1807.8 to 2113.6) |
| 75–84 years | 5525.7 (5137.2 to 5943.7) | 5398.1 (5193.3 to 5610.9) | 1989.6 (1644.1 to 2407.8) | 1857.4 (1668.8 to 2067.3) |
| ≥85 years | 9995.0 (9115.4 to 10 959.5) | 10 122.7 (9694.3 to 10 569.9) | 1730.8 (1222.7 to 2450.1) | 1621.4 (1360.4 to 1932.4) |
| Total | 1885.6 (1835.3 to 1937.2) | 1962.8 (1935.2 to 1990.9) | 4663.5 (4539.5 to 4791.0) | 4055.5 (3991.1 to 4121.0) |
| British Columbia | ||||
| 0–4 years | 2671.6 (2641.9 to 2701.7) | 2464.1 (2442.1 to 2486.3) | 18 639.8 (18 561.0 to 18 719.1) | 13 603.8 (13 552.0 to 13 655.8) |
| 5–17 years | 957.6 (947.3 to 967.9) | 945.2 (937.1 to 953.5) | 7648.4 (7619.4 to 7677.5) | 6205.7 (6184.7 to 6226.8) |
| 18–39 years | 642.2 (636.3 to 648.2) | 634.8 (630.3 to 639.4) | 2225.8 (2214.7 to 2236.9) | 1734.8 (1727.3 to 1742.2) |
| 40–64 years | 1130.9 (1123.8 to 1138.1) | 1183.8 (1178.2 to 1189.4) | 1983.1 (1973.6 to 1992.6) | 1654.7 (1648.1 to 1661.3) |
| 65–74 years | 2430.5 (2407.6 to 2453.6) | 2543.7 (2527.8 to 2559.7) | 1876.0 (1855.9 to 1896.3) | 1686.7 (1673.8 to 1699.8) |
| 75–84 years | 4496.6 (4458.0 to 4535.5) | 4800.3 (4770.4 to 4830.4) | 1942.4 (1917.1 to 1968.0) | 1649.8 (1632.3 to 1667.5) |
| ≥85 years | 8997.4 (8908.9 to 9086.8) | 10 174.5 (10 108.4 to 10 241) | 1968.0 (1926.8 to 2010.1) | 1504.6 (1479.3 to 1530.3) |
| Total | 1446.7 (1441.9 to 1451.6) | 1559.3 (1555.5 to 1563.2) | 3707.0 (3699.2 to 3714.8) | 2852.5 (2847.3 to 2857.7) |