Baseline characteristics
| n | 112 |
| Demographics | |
| Age (years) | 52±14 |
| Height (cm) | 164±18 |
| Weight (kg) | 80±22 |
| Body mass index (kg/m2) | 29.1±7.3 |
| Female | 93 (83%) |
| White | 100 (89%) |
| Aetiology | |
| Idiopathic or familial | 45 (40%) |
| Methamphetamine associated | 20 (18%) |
| Connective tissue disease associated | 27 (24%) |
| Congenital heart disease associated | 20 (18%) |
| Haemodynamics | |
| Right atrial pressure (mm Hg) | 9±6 |
| Mean pulmonary artery pressure (mm Hg) | 47±13 |
| Cardiac index (L/min/m2) | 2.6±0.8 |
| Pulmonary vascular resistance (Wood units) | 8.6±4.8 |
| Markers of severity | |
| 6MWD (m) | 366±107 |
| RV basal diameter (cm) | 4.5±0.8 |
| TAPSE (mm) | 20±5 |
| NYHA Functional Class III/IV | 38 (34%) |
| Treatment | |
| PAH monotherapy | 39 (35%) |
| PAH dual-agent therapy | 54 (48%) |
| PAH triple-agent therapy | 19 (17%) |
| Thyroid replacement therapy | 16 (14%) |
| Treatment for hyperthyroidism | 0 (0%) |
6MWD, 6-minute walk distance; NYHA, New York Heart Association; PAH, pulmonary arterial hypertension; RV, right ventricle; TAPSE, tricuspid annular plane systolic excursion.