Baseline characteristics of survivors and non-survivors
| Characteristics | Total N=2122a | Survivor n=1819a | Non-survivor n=303a | P-valueb |
| ICU admission, n (%) | 216 (10.2) | 169 (9.3) | 47 (15.5) | 0.002 |
| NTBR-No-ICU, n (%) | 558 (26.3) | 347 (19.1) | 211 (69.6) | <0.0001 |
| Age (years), mean (SD) | 68.94 (18.1) | 66.46 (18.0) | 83.8 (9.4) | <0.0001 |
| Female gender, n (%) | 937 (44.2) | 832 (45.7) | 105 (34.7) | 0.0004 |
| Comorbidities, n (%) | <0.0001 | |||
| 0 | 853 (40.2) | 816 (44.8) | 37 (12.2) | |
| 1 | 515 (24.3) | 440 (24.2) | 75 (24.8) | |
| ≥2 | 754 (35.5) | 563 (31.0) | 191 (63) | |
| RR (b/m), mean (SD) | 30.1 (7.8) | 29.58 (7.7) | 32.86 (8.2) | <0.0001 |
| SpO2 (%), mean (SD) | 94.4 (3.6) | 94.5 (3.6) | 93.89 (3.6) | <0.0001 |
| FiO2 (%), mean (SD) | 31.5 (15.9) | 30 (14.3) | 40.57 (21.2) | <0.0001 |
| PaO2/FiO2 (mmHg), mean (SD) | 291.6 (112.2) | 301.1 (111) | 235 (102.4) | <0.0001 |
| sBP (mmHg), mean (SD) | 102.9 (18.6) | 103.5 (18.2) | 98.9 (20.3) | <0.0001 |
| dBP (mmHg), mean (SD) | 64.6 (13.4) | 65.1 (13.2) | 61.8 (14.6) | <0.0001 |
| mBP (mmHg), mean (SD) | 76.8 (13.9) | 77.4 (13.7) | 73.6 (14.6) | <0.0001 |
| Creatinine (mg/dL), mean (SD) | 104.3 (88.3) | 99.1 (86) | 134.6 (95.2) | <0.0001 |
| Urea (mg/dL), mean (SD) | 7.44 (5.6) | 6.8 (4.9) | 11.2 (7.7) | <0.0001 |
| Bilirubin (mg/dL), mean (SD) | 10.1 (18.1) | 9.2 (6.3) | 15.14 (43.8) | <0.0001 |
| Thrombocytes (103 /mm3), mean (SD) | 206.1 (85.2) | 208.8 (82.1) | 190.2 (100.2) | <0.0001 |
| CRP (mg/dL), mean (SD) | 84.7 (77.8) | 79.2 (74.7) | 116.7 (87.8) | <0.0001 |
| qSOFA score, n (%) | <0.0001 | |||
| 0 | 236 (11.1) | 221 (12.2) | 15 (5) | |
| 1 | 1114 (52.5) | 971 (53.4) | 143 (47.2) | |
| ≥2 | 772 (36.4%) | 627 (34.5) | 145 (47.9) | |
| SOFA score, n (%) | <0.0001 | |||
| 0–6 | 2000 (94.3) | 1747 (96) | 253 (83.5) | |
| 7–9 | 112 (5.3) | 69 (3.8) | 43 (14.2) | |
| ≥10 | 10 (0.5) | 3 (0.2) | 7 (2.3) | |
| CURB-65 score, n (%) | <0.0001 | |||
| 0–1 | 896 (42.2) | 852 (46.7) | 44 (14.5) | |
| 2 | 601 (28.3) | 529 (29.1) | 72 (23.8) | |
| ≥3 | 625 (29.4) | 438 (24.1) | 187 (61.7) | |
| 4C score, n (%) | <0.0001 | |||
| 0–3 | 210 (9.9) | 210 (11.5) | 0 | |
| 4–8 | 487 (23) | 483 (26.6) | 4 (1.3) | |
| 9–14 | 1084 (51.1) | 939 (51.6) | 145 (47.9) | |
| ≥15 | 341 (16.1) | 187 (10.3) | 154 (50.8) | |
| ROX score, n (%) | <0.0001 | |||
| <5 | 214 (10.7) | 142 (8.3) | 72 (24.7) | |
| 5–15 | 1134 (56.8) | 964 (56.5) | 170 (58.4) | |
| 15–25 | 576 (28.8) | 532 (31.2) | 44 (15.1) | |
| ≥25 | 74 (3.7) | 69 (4) | 5 (1.7) |
aData is presented as n (%) or mean (standard deviation).
bP-values were calculated from fisher’s exact test or Mann-Whitney-Wilcoxon test.
4C, Coronavirus Clinical Characterisation Consortium; CRP, C reactive protein; CURB-65, Confusion, Uraemia, Respiratory Rate, Blood Pressure and Age ≥65; DBP, diastolic blood pressure; FiO2, fraction of inspired oxygen; ICU, intensive care unit; mBP, Mean blood pressure; NTBR, not to be resuscitated; PaO2, partial pressure of arterial oxygen; qSOFA, Quick Sequential Organ Failure Assessment; ROX, Respiratory Rate and Oxygenation; RR, respiratory rate; SBP, systolic blood pressure; SpO2, percutaneous oxygen saturation.