Documented reasons for discontinuation of IL-5 inhibitor treatment
| Reason for discontinuation | Total |
| Recurrent intensive care unit (ICU) admissions (× 4) | 1 |
| Adverse event—urticaria | 1 |
| Lung cancer diagnosis | 1 |
| Lack of efficacy | 1 |
| Non-adherence, smoking, missed dose | 1 |
| Non-responder | 4 |
| Patient emigrated | 2 |
| Patient refused to continue | 1 |
| Switched to dupilumab | 2 |
| Switched to omalizumab | 1 |
| Planning pregnancy | 1 |
| Death due to severe pre-existing cardiac disease | 1 |
| Death due to pre-existing renal disease | 1 |
| Death due to sudden cardiac death (postmortem results still pending) | 1 |
Reason for discontinuation = documented reason for discontinuation of IL-5 treatment at any point during the 18-month treatment period.
Total = total number of patients discontinued on IL-5 inhibitor treatment for this documented reason.