Table 2

Number of concordant and discordant interpretations for abnormal FVC (FVC<LLN) when using Canadian reference equation compared with GLI-Race or GLI-Other equation*

EthnicityGLI-RaceTotalGLI-OtherTotal
FVC≥LLNFVC<LLNFVC≥LLNFVC<LLN
AllCanadianCanadian
FVC≥LLN293 (72.2%)1 (0.2%)294FVC≥LLN294 (72.4%)0 (0%)294
FVC<LLN56 (13.8%)56 (13.8%)112FVC<LLN56 (13.8%)56 (13.8%)112
Total34957406Total35056406
CaucasianCanadianCanadian
FVC≥LLN186 (81.2%)0 (0%)186FVC≥LLN186 (81.2%)0 (0%)186
FVC<LLN14 (6.1%)29 (12.7%)43FVC<LLN24 (10.5%)19 (8.3%)43
Total20029229Total21019229
BlackCanadianCanadian
FVC≥LLN7 (35.0%)0 (0%)7FVC≥LLN7 (35.0%)0 (0%)7
FVC<LLN10 (50.0%)3 (15.0%)13FVC<LLN5 (25.0%)8 (40.0%)13
Total17320Total12820
NE AsianCanadianCanadian
FVC≥LLN13 (61.9%)1 (4.8%)14FVC≥LLN14 (66.7%)0 (0%)14
FVC<LLN2 (9.5%)5 (23.8%)7FVC<LLN3 (14.3%)4 (19.0%)7
Total15621Total17421
SE AsianCanadianCanadian
FVC≥LLN66 (71.7%)0 (0%)66FVC≥LLN66 (71.7%)0 (0%)66
FVC<LLN20 (21.7%)6 (6.5%)26FVC<LLN14 (15.2%)12 (13.0%)26
Total86692Total801292
Other/MixedCanadianCanadian
FVC≥LLN21 (47.7%)0 (0%)21FVC≥LLN21 (47.7%)0 (0%)21
FVC<LLN10 (22.7%)13 (29.5%)23FVC<LLN10 (22.7%)13 (29.5%)23
Total311344Total311344
  • *We analysed the data by classifying Asian participants as NE Asian (model 1) if they could not be classified clearly as either NE Asian or SE Asian.

  • FVC, forced vital capacity; GLI, Global Lung Function Initiative; LLN, lower limit of normal; NE, North East; SE, South East.