No abnormality | Emphysema | Fibrosis | |||
n=721 | n=158 | P value* | n=465 | P value* | |
FEV1% predicted | 95.4 (17.0) | 79.9 (20.7) | <0.0005 | 88.7 (18.6) | <0.0005 |
FVC % predicted | 99.5 (15.7) | 95.1 (18.1) | 0.002 | 93.1 (18.1) | <0.0005 |
FEV1/FVC ratio | 0.74 (0.1) | 0.64 (12.6) | <0.0005 | 0.73 (0.1) | 0.004 |
DLCO (mls/min/mmHg) | 25.8 (7.2) | 18.4 (6.3) | <0.0005 | 20.3 (0.1) | <0.0005 |
Data are mean (SD)
*Compared with no abnormality group.
DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.