Table 2

Lung function variables stratified by the presence of emphysema, fibrosis (mean, SD)

No abnormalityEmphysemaFibrosis
n=721n=158P value*n=465P value*
FEV1% predicted95.4 (17.0)79.9 (20.7)<0.000588.7 (18.6)<0.0005
FVC % predicted99.5 (15.7)95.1 (18.1)0.00293.1 (18.1)<0.0005
FEV1/FVC ratio0.74 (0.1)0.64 (12.6)<0.00050.73 (0.1)0.004
DLCO (mls/min/mmHg)25.8 (7.2)18.4 (6.3)<0.000520.3 (0.1)<0.0005
  • Data are mean (SD)

  • *Compared with no abnormality group.

  • DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.