Research questions in each of the dominant themes with examples
| 1. Treatment options | What is the best IV bronchodilator therapy and in what order should the IV options be given? What is the utility of NIV and high flow? Which steroid is ‘best’ for exacerbations of asthma, what dosing? What are the risks of giving IV therapy on the ward? What is the role of nebulised magnesium? What is the role of ketamine? How does ipratropium help prevent admission or escalation of care in an acute exacerbation of asthma? What is the role of IM epinephrine? What is the role of Heliox? |
| 2. Diagnosis and classification | What is the usefulness of peak flow in diagnosis and classification of severity? How do you identify those with secondary pneumonia? What is the utility of point of care ultrasound? What should an international clinical practice guideline look like and what are the research goals? |
| 3. What are reasonable treatment goals? | For clinical parameters including respiratory function? What should be the target oxygen level? |
| 4. Questions related to families and children | What are ways in which you can prevent asthma exacerbations? How do you ensure knowledge translation of asthma care plans? |
IV, invasive ventilation; NIV, non-invasive ventilation.