Multivariate weighted regression model analysis reveals the associations between SUA/SCr and lung function parameters
| Non-adjusted model | Minimally adjusted model | Fully adjusted model | |
| β (95% CI) P value | β (95% CI) P value | β (95% CI) P value | |
| FVC | |||
| SUA/SCr | −39.972 (−73.515 to −6.429) 0.0237 | −72.676 (−92.046 to −53.306) <0.0001 | −47.630 (−63.499 to −31.761) <0.0001 |
| SUA/SCr quartile categories | |||
| Q1 | Reference | Reference | Reference |
| Q2 | 77.741 (−5.653 to 161.135) 0.0742 | −79.625 (−127.611 to −31.639) 0.0023 | −66.127 (−113.530 to −18.724) 0.0136 |
| Q3 | 71.472 (−13.480 to 156.423) 0.1060 | −120.115 (−173.522 to −66.708) 0.0001 | −87.273 (−138.182 to −36.365) 0.0035 |
| Q4 | −83.842 (−182.899 to 15.215) 0.1039 | −192.008 (−247.354 to −136.662) <0.0001 | −123.615 (−172.507 to −74.723) 0.0001 |
| P for trend | 0.1135 | <0.0001 | <0.0001 |
| FEV1 | |||
| SUA/SCr | −17.377 (−46.297 to 11.544) 0.2447 | −51.980 (−69.899 to −34.060) <0.0001 | −36.956 (−52.375 to −21.537) 0.0001 |
| SUA/SCr quartile categories | |||
| Q1 | Reference | Reference | Reference |
| Q2 | 64.750 (−1.912 to 131.411) 0.0632 | −61.515 (−100.261 to −22.768) 0.0034 | −54.074 (−93.022 to −15.125) 0.0140 |
| Q3 | 55.559 (−19.283 to 130.401) 0.1525 | −93.760 (−138.237 to −49.282) 0.0002 | −75.024 (−117.771 to −32.278) 0.0029 |
| Q4 | −34.360 (−117.268 to 48.548) 0.4208 | −141.514 (−192.237 to −90.791) <0.0001 | −99.934 (−145.484 to −54.384) 0.0004 |
| P for trend | 0.4315 | <0.0001 | 0.0002 |
| FEV1/FVC | |||
| SUA/SCr | 0.003 (0.001 to 0.006) 0.0064 | 0.001 (−0.001 to 0.003) 0.2161 | −0.000 (−0.002 to 0.002) 0.9469 |
| SUA/SCr quartile categories | |||
| Q1 | Reference | Reference | Reference |
| Q2 | 0.001 (−0.004 to 0.006) 0.7578 | −0.000 (−0.005 to 0.005) 0.9865 | −0.001 (−0.005 to 0.004) 0.7059 |
| Q3 | 0.001 (−0.005 to 0.006) 0.8214 | 0.001 (−0.004 to 0.006) 0.7602 | −0.001 (−0.006 to 0.004) 0.7037 |
| Q4 | 0.008 (0.000 to 0.015) 0.0422 | 0.002 (−0.003 to 0.008) 0.4559 | −0.001 (−0.006 to 0.005) 0.7503 |
| P for trend | 0.0599 | 0.4324 | 0.7492 |
Non-adjusted model adjusted for none.
Minimally adjusted model adjusts for gender, age and race/ethnicity.
Fully adjusted model adjusts for gender, age, race/ethnicity, education level, poverty income ratio, marital status, physical activity, body mass index, hypertension history, diabetes history, respiratory disease history had at least 12 alcohol drinks/year, smoked at least 100 cigarettes in life, foods of affecting SUA eaten during past 30 days, serum calcium, phosphorus, total bilirubin, total protein, aspartate aminotransferase, alkaline phosphatase, total cholesterol and glycohaemoglobin.
FEV1, forced expiratory volume in one second; FVC, forced vital capacity; SCr, serum creatinine; SUA, serum uric acid.