Table 1

Existing human trials previously published (only relevant inhaled route is shown)

ReferenceYearIndicationAetiologyDelivery methodEfficacy
Delacoste631959Refractory coughsNAInhalation100%
Hoeflmayr et al641962BronchitisStreptococci (2/3); Staphylococci (1/3)Inhalation90%
Garsevanishvili651974PneumoniaStaphylococci, streptococci and enterococci were targetedInhalationN/A
Ioseliani et al661980Lung infectionsStaphylococci and/or othersInhalation, bronchoscopy>90%
Meladze et al671982Parenchyma and pleura infectionsStaphylococcusInhalation, topical, parenteral>90% (223)
Kvachadze et al682011Cystic fibrosis-associated infectionsStaphylococcus and PseudomonasInhalationImprovement
  • This table was adapted from Abedon et al. These studies that have been cited may be in languages other than English and therefore are obtained from a summarised review article that has been published in English.69