Table 2

Initial evaluation and outcome measurements of functional capacity, mental health and health related quality of life

GroupBaseline8 weeksPre–post differencePre–post significanceBetween-groups significance at 8 weeks
6MWT (m)
 Rehab451.5±109.2513.3±102.761.77±39.11p<0.001*p=0.501
 UC408.3±85.7466.2±83.457.95±67.09p<0.001*
SPPB
 Rehab9.85±1.9511.46±0.881.62±1.26p=0.001*p=0.002*
 UC9.15±1.579.95±1.510.80±1.11p=0.004*
HADS-A
 Rehab7.08±4.035.0±3.87−2.08±1.71p=0.001*p=0.013*
 UC6.06±3.567.06±4.651.00±3.65p=0.261
HADS-D
 Rehab5.31±1.974.23±3.22−1.08±2.29p=0.105p=0.627
 UC6.39±5.375.44±4.49−0.94±4.14p=0.319
IES-R (PTSD)
 Rehab1.25±0.790.97±0.71−0.29±0.42p=0.028*p=0.135
 UC1.14±0.871.22±1.020.08±0.74p=0.660
BDI
 Rehab9 (15)3 (10)−8 (7)p=0.001*p=0.017*
 UC12 (14)11 (17)0 (5)p=0.938
MoCA
 Rehab25 (5)29 (2)3 (4)p=0.008*p<0.001*
 UC25 (6)25 (6)1 (2)p=0.046*
EQ-5D-5L (UI)
 Rehab0.59±0.180.85±0.110.26±0.19p<0.001*p=0.001*
 UC0.62±0.250.66±0.230.04±0.17p=0.372
EQ-5D-5L (VAS)
 Rehab68.46±16.6381.1±10.412.6±12.1p=0.003*p=0.043*
 UC69.44±15.9975.0±11.75.5±12.8p=0.084
  • Data are presented as mean±SD for parametric or as median (IQR) for non-parametric data. Baseline evaluation was within 6–8 weeks post-hospital discharge. Pre–post significance within groups was evaluated by paired t-tests for parametric data or Wilcoxon signed rank tests for non-parametric data. Outcome comparisons at 8 weeks between groups were performed with univariate analysis of covariance using baseline values as covariates.

  • *Denotes statistical significance between groups (p<0.05).

  • BDI, Beck Depression Inventory; EQ-5D-5L UI, EuroQol Utility Index; HADS, Hospital Anxiety and Depression Scale; IES-R, Impact of Event Scale, Revised; MoCA, Montreal Cognitive Assessment; 6MWT, 6-min walking test; PTSD, post-traumatic stress disorder; Rehab, rehabilitation group; SPPB, Short Physical Performance Battery; UC, usual care group; VAS, Visual Analogue Scale.