Demographic and clinical information regarding participants with and without interstitial lung disease
| Interstitial lung disease (known or newly diagnosed) | No interstitial lung disease | Comparison (p value) | |||
| Number of participants, % of overall eligible cohort | 66 | 1% | 6584 | 99% | |
| Age, years, mean, SD | 72.6 | 6.3 | 68.4 | 7.0 | <0.0001 |
| Male, n, % | 50 | 76% | 3618 | 55% | 0.001 |
| IMD rank, median, IQR (lower=more deprived) | 13 838 | 3907–21 622 | 3605–21 916 | 0.885 | |
| mMRC dyspnoea score, n, % | 0.435 | ||||
| 0–1 | 51 | 77% | 5384 | 82% | |
| 2–4 | 15 | 23% | 1200 | 18% | |
| WHO performance status, n, % | 0.108 | ||||
| 0–1 | 56 | 85% | 6008 | 91% | |
| 2–3 | 10 | 15% | 576 | 9% | |
| Smoking status, n, % | 0.491 | ||||
| Current (within the last month) | 20 | 30% | 2313 | 35% | |
| Ex-smoker | 46 | 70% | 4271 | 65% | |
| Smoking history (pack years), median, IQR | 32 | 22–47 | 35 | 26–45 | 0.447 |
| Spirometry, mean, SD | |||||
| FEV1 (L) | 2.2 | 0.7 | 2.2 | 0.7 | 0.642 |
| FEV1 % predicted | 93 | 26 | 89 | 21 | 0.317 |
| FVC (L) | 3.1 | 0.9 | 3.2 | 0.9 | 0.569 |
| FVC % predicted | 99 | 23 | 103 | 20 | 0.259 |
| Screen-detected lung cancer, n, % | 5 | 7.5% | 158 | 2.4% | 0.015 |
FEV1, forced expiratory volume in one second; FVC, forced vital capacity; IMD, Index of Multiple Deprivation; mMRC, modified Medical Research Council.