A | Prevalence of clinically-diagnosed asthma | 3 800 000 people |
SABA overuse | ||
Mild overuse: >150 to 375 uses (doses)of SABA per year* | ||
MDI | ||
B | Number of people in ‘A’ who use a SABA MDI >150 to 375 times per year | 750 120 people |
C | Carbon footprint associated with excess SABA MDI use in people in ‘B’ | 22 194 MT CO2e |
Moderate overuse: >375 to 750 uses of SABA per year* | ||
MDI | ||
D | Number of people in ‘A’ who use a SABA MDI >375 to 750 times per year | 250 040 people |
E | Carbon footprint associated with excess SABA MDI use in people in ‘D’ | 27 126 MT CO2e |
Severe overuse: >750 usesof SABA per year* | ||
MDI | ||
F | Number of people in ‘A’ who use a SABA MDI>750 times per year | 71 440 people |
G | Carbon footprint associated with excess SABA MDI use in people in ‘F’ | 11 273 MT CO2e |
Total | ||
H | Carbon footprint of SABA MDI overuse | 60 594 MT CO2e |
I | Carbon footprint of SABA DPI overuse – online supplemental appendix B, table S1 | 132 MT CO2e |
J | Total carbon footprint of SABA inhaler overuse | 60 726 MT CO2e |
Detailed calculations, supportive information and additional data on DPIs are presented in online supplemental material 1, appendix B, table S1
*Overuse is defined as requiring >150 uses (doses) of a SABA over a year.31 This reflects a conservative definition, given that guidelines define well-controlled asthma as no more than two uses (doses) of SABA per week.24 25 Note that a typical use (dose) of a SABA MDI consists of two medication actuations, and of a SABA DPI consists of one medication actuation). Categories of people overusing SABA are derived from Nwaru, Ekstrom.31 We calculated the mid-point estimate for mild and moderate SABA overuse categories, and the low-point estimate for the severe overuse category. We did not count the first 150 uses (doses) in any category, as those doses are considered within the acceptable limit for good asthma control.
DPI, dry powder inhaler; MDI, metred-dose inhaler; MT CO2e, metric tons of CO2 equivalent; SABA, short-acting beta2-agonist.