Table 2

Subgroup analyses according to possible factors that may modify the association between insomnia and asthma

Characteristics of studiesNumber of studiesOR with 95% CIHeterogeneity (%)
Cohort studies6 7 21 29 3251.73 (1.16 to 2.57)93.3
Cross-sectional studies8–17 19 20 30 31 33–36181.20 (1.14 to 1.28)54.9
Insufficient sleep duration8 9 11 13–17 19–21 30 31 33141.20 (1.13 to 1.28)56.1
Poor sleep quality8–12 29 3471.10 (1.05 to 1.16)0
Adults6–8 14 17 20 31 33 34 36101.36 (1.18 to 1.57)56.4
Adolescents10 15 16 19 21 29 30 3581.15 (1.08 to 1.21)59.8
Children9 11 1231.13 (0.97 to 1.32)14.7
Studies conducted in Europe and America7 11 19–21 31 34 3581.34 (1.21 to 1.48)22.2
Studies conducted in Asia6 8–10 12–16 29 32111.21 (1.12 to 1.31)79.8
Studies in which BMI was adjusted7 9 13–16 20 21 30 33 34111.22 (1.13 to 1.31)62.7
Studies in which BMI was not adjusted6 8 10–12 17 19 29 31 32 35 36121.29 (1.14 to 1.47)79.4
Studies in which family history of asthma was adjusted12 2121.16 (0.94 to 1.42)53.1
Studies in which family history of asthma was not adjusted6–11 13–17 19 20 29–36211.27 (1.18 to 1.36)76.1
  • BMI, body mass index.