Hyperoxia | No hyperoxia | OR | 95% CI | |
Age | ||||
<65 years | 4.9% (0.0–11.5%) | 11.4% (2.0–20.7%) | 0.40 | 0.73 to 2.19 |
≥65 years | 38.1% (28.8–47.4%) | 21.5% (14.2–28.8%) | 2.25 | 1.25 to 4.04 |
Chronic cardiopulmonary disease* | ||||
(−) | 28.8% (21.1–36.5%) | 14.0% (8.1–19.8%) | 2.49 | 1.35 to 4.60 |
(+) | 26.7% (4.3–49.0%) | 39.3% (21.2–57.4%) | 0.56 | 0.14 to 2.22 |
Source of infection confirmed | ||||
Pulmonary | 12.8% (2.3–23.3%) | 18.2% (2.1–34.3%) | 0.66 | 0.16 to 2.78 |
Extrapulmonary | 34.3% (25.3–43.2%) | 18.9% (12.5–25.3%) | 2.24 | 1.26 to 3.99 |
Septic shock | ||||
(−) | 29.0% (20.4–37.6%) | 17.2% (10.5–23.9%) | 1.96 | 1.05 to 3.68 |
(+) | 27.5% (13.7–41.3%) | 23.3% (10.6–35.9%) | 1.25 | 0.47 to 3.37 |
Without hypoxia† | 28.8% (21.4–36.1%) | 18.8% (12.8–24.7%) | 1.75 | 1.03 to 2.97 |
IPW analyses were performed in each subgroup.
*Chronic cardiopulmonary diseases included congestive heart failure, coronary artery disease and chronic lung diseases.
†Hypoxia was defined as PaO2 <60 mm Hg.
IPW, inverse probability weighting; PaO2, arterial partial pressure of oxygen.