Table 5

Percentage of adults with chronic obstructive pulmonary disease who switched, stepped-down or stepped-up respiratory pharmacological treatment after the first-line treatment (broad definition)

LabelCCAE (USA)Medicaid (USA)Medicare (USA)EHIF (Estonia)CPRD (UK)SIDIAP (Spain)IPCI (The Netherlands)AUSOM
(South Korea)
Step-up10.213.412.023.532.928.024.613.7
Step-down6.67.87.513.713.314.612.116.6
Switching8.611.39.49.225.417.010.89.6
Start of acute exacerbation17.415.615.010.310.813.014.99.7
End of acute exacerbation18.215.415.64.26.08.112.17.5
No follow-up treatment*39.036.540.439.011.619.325.643.0
Other0.040.010.01
  • *Patients who did not receive medication of a different respiratory drug class after the first treatment, that is, patients who remained on the same treatment or who discontinued treatment.