Elsevier

Life Sciences

Volume 31, Issue 8, 23 August 1982, Pages 791-794
Life Sciences

Regulation of glucose metabolism in the lung: Hexokinase-catalyzed phosphorylation, a rate-limiting step

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Abstract

A measurement of uptake and phosphorylation of 2-deoxyglucose in rat lung slices under appropriately designed conditions showed that glucose metabolism in lung at the physiological concentration of the sugar will be limited by the rate of its phosphorylation and not by its transport into the cells.

References (11)

  • L. Grossbard et al.

    J. Biol. Chem.

    (1966)
  • R.G. Kemp

    Methods Enzymol.

    (1975)
  • T. Bucher et al.

    Methods Enzymol.

    (1955)
  • R.F. Fricke et al.

    J. Biol. Chem.

    (1979)
  • R.F. Kletzien et al.

    J. Biol. Chem.

    (1972)
There are more references available in the full text version of this article.

Cited by (0)

1

Present address: Department of Physiological Chemistry and Pharmacology, Roche Institute of Molecular Biology, Nutley, New Jersey 07110 USA

2

Present address: Department of Clinical Nutrition, HoffmannLa Roche Inc, Nutley, New Jersey 07110 USA

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