Original articleEffect of vitamin E deficiency on neurologic function in patients with cystic fibrosis
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Cited by (27)
Association between fat-soluble nutrient status and auditory and visual related potentials in newly diagnosed non-screened infants with cystic fibrosis: A case-control study
2019, Prostaglandins Leukotrienes and Essential Fatty AcidsCitation Excerpt :We cannot exclude the possibility that CFTR dysfunction in neurons contributes to the observed phenotype. Consistent with this hypothesis, Reznikov et al. showed in Cftr-null newborn pigs that loss of CFTR resulted in features of both axonal and demyelinating neuropathy, recapitulating those reported in the adolescent/adult CF population [56–58]. Interestingly, in the Cftr-null animals, AEPs latencies were prolonged compared to non-CF animals meaning that cognitive responses were delayed [59].
Methods for assessment of vitamin E
2018, Laboratory Assessment of Vitamin StatusPeripheral neuropathy in cystic fibrosis: A prevalence study
2013, Journal of Cystic FibrosisCitation Excerpt :Clinical research criteria for distal symmetrical polyneuropathy were not met as none of the patients had any clinical evidence of muscle weakness or atrophy [18]. This finding is compatible with previous studies [8–10]. This study evaluated electrophysiological peripheral neuropathy in cystic fibrosis patients with appropriate sample size in a detailed and comprehensive manner in a wide age group range (1–18 years).
Nutrition Management of Pediatric Patients Who Have Cystic Fibrosis
2009, Pediatric Clinics of North AmericaCitation Excerpt :Vitamin E requires bile, pancreatic juices, and dietary fat for optimal absorption, thereby putting patients with CF at risk for vitamin E deficiency if they do not receive adequate supplementation. Oxidative stress and a diet high in polyunsaturated fatty acids (PUFAs) may increase vitamin E needs in CF.31 Reports of vitamin deficiency and its subsequent neurologic consequences in persons with CF have appeared in the literature32,33 but are less common since the development of CF-specific multivitamins containing increased amounts of vitamin E. Low levels of vitamin E have been reported in PS patients.34,35 Vitamin deficiency is present at the time of diagnosis in infants identified through newborn screening,36 which, in some patients, continues into childhood.37
Vitamin E and Vitamin K Metabolism
2006, Physiology of the Gastrointestinal TractElectrophysiologic recovery after vitamin E - Deficient neuropathy
1999, Archives of Physical Medicine and Rehabilitation