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ORIGINAL RESEARCHCYSTIC FIBROSISThe Association Between Depression, Lung Function, and Health-Related Quality of Life Among Adults With Cystic Fibrosis
Section snippets
Materials and Methods
This was a cross-sectional study that was conducted from April 2002 to November 2003. Adults ≥ 18 years of age were eligible to be included if they had a confirmed diagnosis of CF, had been seen in the clinic previously, and were scheduled for an outpatient appointment. A recruiter telephoned the patient, explained the study, assessed eligibility, and obtained verbal consent to mail the study materials. Participants completed the questionnaires at home and mailed back the consent form and
Results
One hundred thirty-three patients met the study eligibility requirements. Of these, 109 patients (82%) verbally consented, 11 (8%) refused consent, 7 (5%) were unable to be contacted, and 6 (5%) died before being contacted. Of the 109 participants, 80 (73%) returned the survey and 1 (1%) died before completing the survey. Two participants who returned completed surveys failed to return a consent form, one person had missing lung function data, and one person had missing depression data; they
Discussion
Consistent with previous studies,178 our study found that depressive symptoms are common among adults with CF, with 30% of participants exhibiting signs of depressive symptoms and 11% of participants screening positive for moderate-to-severe levels of depression. Only 13% of those participants who screened positively for moderate-to-severe levels of depressive symptoms were currently receiving treatment, suggesting that depression may be underdiagnosed and untreated in this population. Although
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2022, Archives of Gerontology and GeriatricsCitation Excerpt :Globally, more than 264 million people suffer from depression (James et al., 2018). In patients with chronic lung diseases, accumulated evidence has indicated that symptoms of depression are inversely related to lung function, as well as a lower adherence to treatment, poorer quality of life, and a higher probability of death (Atlantis et al., 2013; Riekert et al., 2007; Smith et al., 2006). Moreover, two studies conducted in America and Germany both reported that depressive symptoms and lung function were inversely correlated among patients with cystic fibrosis (Goldbeck et al., 2010; Riekert et al., 2007).
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This research was supported by National Institute of Diabetes and Digestive and Kidney Disease grant 61135 and National Heart, Lung, and Blood Institute grant 63333.
The authors have reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.