Chest
Clinical Investigations: Ron/HoscopyEndoscopic Treatment of Malignant Airway Obstructions in 2,008 Patients
Section snippets
Materials and Methods
From April 1982 to December 1994, 2,008 patients with obstructions of the airway due to malignant tumors were treated endoscopically by the first author only (1,838 patients underwent laser resection of which 173 were followed by stent placement and 29 by endoluminal brachytherapy, 133 were stented without any other treatment, and 37 received brachytherapy alone), for a total of 2,798 procedures. At the beginning of our experience, only patients already treated by the oncologist with poor
Results
From April 1982 to December 1994, we performed 4,381 Nd:YAG laser endoscopic resections and 3,133 (in 2,190 patients) were for lung tumors; 2,610 treatments were performed in 1,838 patients with lung cancer
Immediate results were assessed according to the classification criteria proposed by Unger27 and Dumon et al:28 good results were obtained in 93% of patients with bronchogenic carcinoma (Table 6). Poor results were related to the presence of extrinsic compression or to extensive infiltrations
Discussion
Endoscopic resection of tracheobronchial malignancies is mainly devoted to reduce respiratory distress by giving a patent airway to the patient and improve his or her quality of life. Although palliation could be achieved also by mechanical debridement, cryotherapy and photodynamic therapy,33, 34, 35, 36, 37, 38, 39 Nd:YAG laser allows quick and better results in terms of immediate and medium-term palliation. In fact, before laser became available at our institution, we performed 33 mechanical
References (51)
- et al.
Effect of radiation therapy on bronchial obstruction due to bronchogenic carcinoma
Chest
(1989) - et al.
Treatment of tracheobronchial lesions by laser photoresection
Chest
(1982) - et al.
Nd:YAG laser in lung cancer
Ann Thorac Surg
(1987) Treatment of malignant tracheobronchial obstruction
Ann Thorac Surg
(1989)- et al.
Role of phototherapy, brachtherapy and prosthetic stents in the management of lung cancer
- et al.
Complications associated with brachytherapy alone or with laser in lung cancer
Chest
(1991) Lasers, brachytherapy and stents: keeping the airway open
Respir Med
(1991)- et al.
Indication and technique for YAG laser resection in bronchology: a critical analysis based on 2,285 resections
J Thorac Cardiovasc Surg
(1986) - et al.
Nd:YAG laser bronchoscopy: A 5-year experience with 1,396 applications in 1,000 patients
Chest
(1988) A dedicated tracheobronchial stent
Chest
(1990)
Nd:YAG lasertherapy for malignant and benign endobronchial obstructions
Clin Chest Med
Principles for safety in the application of neodynium-YAG laser in bronchology
Chest
Complications of Nd:YAG laser therapy
Chest
Complications of general anesthesia for Nd:YAG laser resection of endobronchial tumors
Chest
Endoscopic relief of malignant airway obstructions
Ann Thorac Surg
Bronchoscopic cryotherapy for airway strictures caused by tumors
Chest
Cryosurgery in bronchoscopic treatment of tracheobronchial stenosis: indications, limits, personal experience
Chest
Hematoporphyrin derivative phototherapy in the treatment of bronchogenic carcinoma
Chest
Photodynamic therapy in the palliation of late stage obstructing non small cell lung cancer
Chest
Survival experience following Nd:YAG laser photoresection for primary bronchogenic carcinoma
Chest
A 2-year experience with the neodymium YAG laser in endobronchial obstructions
Chest
Survival characteristics after neodymium: YAG laser photoresection in advanced stage lung cancer
Chest
Use of Gianturco self-expandable stents in the tracheobronchial tree
Ann Thorac Surg
High dose rate intraluminal irradiation in bronchogenic carcinoma: techniques and results
Chest
Remote after loading brachytherapy for the local control of endobronchial carcinoma
Int J Radiat Oncol Biol Phys
Cited by (377)
The role of interventional bronchoscopy in the management of malignant central airway obstruction
2024, Respiratory Medicine Case ReportsRetrospective study of outcomes after extended resection for tracheobronchial adenoid cystic carcinoma
2023, Journal of Thoracic and Cardiovascular SurgeryCitation Excerpt :Poor local control was associated with worse metastatic progression in patients with ear-nose-throat ACC.26,27,31,32 Repeated endoscopic interventions (eg, laser resection, brachytherapy, and/or stenting) have not provided long-term control of TBACC.33 There is no consensus to date about the best management of large TBACC, notably those classified T4.
Non-infectious respiratory emergencies in patients with cancer
2023, Revue des Maladies RespiratoiresBronchoscopic management of malignant central airway obstructions
2023, Revue des Maladies RespiratoiresL'endoscopie interventionnelle (désobstruction et prothèse)
2022, Revue des Maladies Respiratoires Actualites
revision accepted July 5.