Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma

FASEB J. 2001 May;15(7):1212-4. doi: 10.1096/fj.00-0742fje.
No abstract available

MeSH terms

  • Asthma / pathology
  • Asthma / physiopathology*
  • Bronchi / pathology
  • Bronchi / physiology*
  • Bronchial Provocation Tests
  • Bronchoalveolar Lavage Fluid / chemistry*
  • Cells, Cultured
  • Chemokine CCL5 / metabolism
  • Humans
  • Interleukin-6 / metabolism
  • Lysophospholipids*
  • Models, Biological
  • Muscle, Smooth / pathology
  • Muscle, Smooth / physiology*
  • Signal Transduction / physiology
  • Sphingosine / analogs & derivatives
  • Sphingosine / metabolism*
  • Tumor Necrosis Factor-alpha / metabolism

Substances

  • Chemokine CCL5
  • Interleukin-6
  • Lysophospholipids
  • Tumor Necrosis Factor-alpha
  • sphingosine 1-phosphate
  • Sphingosine