Abstract
A prospective study of false-positive cultures of Mycobacterium tuberculosis that resulted from laboratory cross-contamination was conducted at three laboratories in California. Laboratory cross-contamination accounted for 2% of the positive cultures. Cross-contamination should be a concern when an isolate matches the genotype of another sample processed during the same period.
Publication types
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Multicenter Study
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Typing Techniques / standards
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DNA Fingerprinting
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DNA, Bacterial / genetics
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Diagnostic Errors* / prevention & control
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Equipment Contamination* / prevention & control
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False Positive Reactions
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Humans
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Laboratories / standards*
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Mycobacterium tuberculosis / classification
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Mycobacterium tuberculosis / growth & development
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Mycobacterium tuberculosis / isolation & purification*
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Polymorphism, Restriction Fragment Length
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Specimen Handling
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Tuberculosis / diagnosis*
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Tuberculosis / microbiology*