Management of malignant pleural effusion associated with trapped lung syndrome

Asian Cardiovasc Thorac Ann. 2008 Apr;16(2):120-3. doi: 10.1177/021849230801600208.

Abstract

Management of recurrent malignant pleural effusion associated with trapped lung syndrome remains problematic. An alternative treatment using a pleural catheter has been advocated. Between August 1999 and August 2002, 127 patients underwent thoracoscopy for malignant pleural effusion. Of these, 52 (41%) with trapped lung were managed by insertion of a pleural catheter. Mean age was 66 years (range, 42-89 years). The most frequent diagnosis was breast cancer. Spontaneous pleurodesis (drainage < 10 mL) occurred in 25 (48%) patients whose catheter was removed after 30 to 255 days (mean, 93.8 days). Symptomatic relief was achieved in 49 (94%) patients. Mean dyspnea score improved significantly from 3.0 to 1.9. Complications comprised catheter blockage, surgical emphysema, cellulitis, and loculated effusion in 2 patients each. Mean length of hospital stay was 3 days (range, 1-16 days). Median survival was 126 days (range, 10-175 days). We conclude that long-term placement of a pleural catheter provides effective palliation for malignant pleural effusion associated with trapped lung syndrome.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / complications
  • Breast Neoplasms / therapy
  • Catheters, Indwelling*
  • Drainage / adverse effects
  • Drainage / instrumentation*
  • Dyspnea / etiology
  • Dyspnea / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Length of Stay
  • Lung Diseases / complications
  • Lung Diseases / etiology*
  • Lung Diseases / mortality
  • Lung Diseases / pathology
  • Lung Diseases / therapy
  • Male
  • Mesothelioma / complications
  • Mesothelioma / therapy
  • Middle Aged
  • Palliative Care*
  • Patient Compliance
  • Patient Selection
  • Pleural Effusion, Malignant / complications
  • Pleural Effusion, Malignant / etiology
  • Pleural Effusion, Malignant / mortality
  • Pleural Effusion, Malignant / pathology
  • Pleural Effusion, Malignant / therapy*
  • Pleurodesis
  • Quality of Life
  • Recurrence
  • Syndrome
  • Thoracic Surgery, Video-Assisted
  • Time Factors
  • Treatment Outcome