Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions

Hidenori Mizugaki; Naofumi Shinagawa; Kakuko Kanegae; Noriyuki Yamada; Hajime Asahina; Eiki Kikuchi; Satoshi Oizumi; Nagara Tamaki; Masaharu Nishimura

doi:10.1016/j.lungcan.2009.06.004

Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions

Lung Cancer. 2010 May;68(2):211-5. doi: 10.1016/j.lungcan.2009.06.004.

Authors

Hidenori Mizugaki¹, Naofumi Shinagawa, Kakuko Kanegae, Noriyuki Yamada, Hajime Asahina, Eiki Kikuchi, Satoshi Oizumi, Nagara Tamaki, Masaharu Nishimura

Affiliation

¹ First Department of Medicine, Hokkaido University School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan.

PMID: 19595471
DOI: 10.1016/j.lungcan.2009.06.004

Abstract

To evaluate the combination of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS) and positron emission tomography with fluorodeoxyglucose (FDG-PET) for the diagnosis of small peripheral pulmonary lesions (PPLs) < or = 30 mm in mean diameter. A total of 74 PPLs (69.2%) were diagnosed by TBB using EBUS-GS with X-ray fluoroscopy. Diagnostic yield by FDG-PET was 78.5% for the 107 PPLs examined. Diagnostic yield with the combination of TBB using EBUS-GS and FDG-PET (90.7%) was significantly higher compared with that for each procedure alone. A significant increment in diagnostic yield with this combination was seen for PPLs >20mm and < or = 30 mm and for malignant lesions. Combination of TBB using EBUS-GS and FDG-PET is useful for the diagnosis of small PPLs.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / diagnosis*
Adenocarcinoma / pathology
Adenocarcinoma / physiopathology
Aged
Biopsy
Bronchi / diagnostic imaging
Bronchi / pathology*
Bronchography*
Carcinoma, Squamous Cell / diagnosis*
Carcinoma, Squamous Cell / pathology
Carcinoma, Squamous Cell / physiopathology
Diagnosis, Differential
Endosonography
Humans
Image Interpretation, Computer-Assisted / methods
Lung Neoplasms / diagnosis*
Lung Neoplasms / pathology
Lung Neoplasms / physiopathology
Male
Middle Aged
Multiple Pulmonary Nodules / diagnosis*
Multiple Pulmonary Nodules / pathology
Multiple Pulmonary Nodules / physiopathology
Positron-Emission Tomography
Pulmonary Disease, Chronic Obstructive / diagnosis*
Pulmonary Disease, Chronic Obstructive / pathology
Pulmonary Disease, Chronic Obstructive / physiopathology