Does use of coils in addition to amplatzer vascular plugs prevent recanalization?

AJR Am J Roentgenol. 2010 Sep;195(3):766-71. doi: 10.2214/AJR.09.3953.

Abstract

Objective: Recanalization has been reported with the use of a type 1 Amplatzer vascular plug as the sole device to manage a pulmonary arteriovenous malformation (PAVM). We evaluated our experience with the use of at least one coil in addition to the vascular plug whenever possible in the treatment of patients with a PAVM.

Materials and methods: Thirty patients had 39 feeder vessels in 37 PAVMs managed with 39 type 1 Amplatzer vascular plugs. Eleven PAVMs (30%) were complex, and 26 (70%) were simple; nine (24%) were solitary. CT examinations were scheduled for 6 months after treatment and every 3-5 years thereafter. Scans were evaluated for persistent sac perfusion, sac shrinkage, and/or complete resolution of the PAVM.

Results: Complete occlusion of all PAVMs was achieved. The mean number of coils used in addition to a type 1 Amplatzer vascular plug was 1.5 (range, 0-5 coils). Six patients did not participate in follow-up; 24 patients with 28 PAVMs managed with type 1 Amplatzer vascular plugs underwent follow-up imaging (mean, 13 months after treatment; range, 6-40 months). No PAVM exhibited recanalization at follow-up CT. Sac shrinkage or disappearance was found in all cases, and the plug had a characteristic CT appearance. Longer-term surveillance imaging was scheduled for all patients.

Conclusion: Used in conjunction with coils, the type 1 Amplatzer vascular plug offers excellent occlusion of PAVMs. No recanalization was found in this study.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arteriovenous Malformations / diagnostic imaging
  • Arteriovenous Malformations / therapy*
  • Embolization, Therapeutic / instrumentation*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pulmonary Artery / abnormalities
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Veins / abnormalities
  • Pulmonary Veins / diagnostic imaging
  • Retrospective Studies
  • Secondary Prevention
  • Septal Occluder Device*
  • Telangiectasia, Hereditary Hemorrhagic / diagnostic imaging
  • Telangiectasia, Hereditary Hemorrhagic / therapy*
  • Tomography, X-Ray Computed
  • Treatment Outcome*