Abstract
We describe the success of adjunctive bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection in the context of bilateral ureteric stents and bladder ulceration, after repeated failure of antibiotics alone. No bacteriophage-resistant bacteria arose, and the kinetics of bacteriophage and bacteria in urine suggest self-sustaining and self-limiting infection.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Bacteriophages / immunology*
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Colony Count, Microbial
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Female
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Humans
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Polymerase Chain Reaction
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Pseudomonas Infections / immunology
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Pseudomonas Infections / microbiology*
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Pseudomonas Infections / therapy
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Pseudomonas Infections / urine
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Pseudomonas aeruginosa / genetics
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Pseudomonas aeruginosa / immunology*
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RNA, Ribosomal, 16S / chemistry
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RNA, Ribosomal, 16S / genetics
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Urinary Tract Infections / immunology
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Urinary Tract Infections / microbiology*
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Urinary Tract Infections / therapy
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Urinary Tract Infections / urine
Substances
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DNA, Bacterial
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RNA, Ribosomal, 16S