Aortic root dilatation in Marfan's syndrome: a contribution from obstructive sleep apnea?

P A Cistulli; I Wilcox; R Jeremy; C E Sullivan

doi:10.1378/chest.111.6.1763

Aortic root dilatation in Marfan's syndrome: a contribution from obstructive sleep apnea?

Chest. 1997 Jun;111(6):1763-6. doi: 10.1378/chest.111.6.1763.

Authors

P A Cistulli¹, I Wilcox, R Jeremy, C E Sullivan

Affiliation

¹ Sleep Disorders Centre, Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

PMID: 9187207
DOI: 10.1378/chest.111.6.1763

Abstract

We report two cases of Marfan's syndrome with coexistent obstructive sleep apnea (OSA) in which treatment with nasal continuous positive airway pressure was associated with attenuation of aortic root dilatation, a serious complication of the syndrome. We speculate that coexistent OSA promotes progressive aortic dilatation in some patients with Marfan's syndrome.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Adolescent
Adult
Aorta / pathology*
Dilatation, Pathologic / complications
Dilatation, Pathologic / diagnosis
Dilatation, Pathologic / therapy
Female
Humans
Male
Marfan Syndrome / complications*
Marfan Syndrome / therapy
Positive-Pressure Respiration
Sleep Apnea Syndromes / complications*
Sleep Apnea Syndromes / therapy