Nasal gene expression of angiotensin-converting enzyme 2 in children and adults
S Bunyavanich, A Do, A Vicencio - Jama, 2020 - jamanetwork.com
We found age-dependent ACE2 gene expression in nasal epithelium (Figure). ACE2 gene
expression was lowest (mean log2 counts per million, 2.40; 95% CI, 2.07-2.72) in younger …
expression was lowest (mean log2 counts per million, 2.40; 95% CI, 2.07-2.72) in younger …
Conditional overexpression of bioactive transforming growth factor–β1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia?
AG Vicencio, CG Lee, SJ Cho, O Eickelberg… - American journal of …, 2004 - atsjournals.org
Research interest in bronchopulmonary dysplasia (BPD) has steadily increased, and
numerous potential mediators have been implicated in the development of the disease …
numerous potential mediators have been implicated in the development of the disease …
TGF‐β signaling is dynamically regulated during the alveolarization of rodent and human lungs
MA Alejandre‐Alcázar… - … dynamics: an official …, 2008 - Wiley Online Library
Although transforming growth factor‐beta (TGF‐β) signaling negatively regulates branching
morphogenesis in early lung development, few studies to date have addressed the role of …
morphogenesis in early lung development, few studies to date have addressed the role of …
Racial/ethnic variation in nasal gene expression of transmembrane serine protease 2 (TMPRSS2)
S Bunyavanich, C Grant, A Vicencio - Jama, 2020 - jamanetwork.com
Methods| This cross-sectional study used nasal epithelium collected during 2015-2018 from
individuals within the Mount Sinai Health System (New York, New York), a cohort we have …
individuals within the Mount Sinai Health System (New York, New York), a cohort we have …
Lower airway microbiota and mycobiota in children with severe asthma
REFERENCES 1. Gudjonsson JE, Ding J, Li X, Nair RP, Tejasvi T, Qin ZS, et al. Global gene
expression analysis reveals evidence for decreased lipid biosynthesis and increased innate …
expression analysis reveals evidence for decreased lipid biosynthesis and increased innate …
Fungal sensitization in childhood persistent asthma is associated with disease severity
AG Vicencio, MT Santiago, K Tsirilakis… - Pediatric …, 2014 - Wiley Online Library
Rationale Recent observations, especially in adults, suggest that asthma severity may be
associated with fungal sensitization. Other studies suggest that some patients with severe …
associated with fungal sensitization. Other studies suggest that some patients with severe …
[HTML][HTML] Integrative study of the upper and lower airway microbiome and transcriptome in asthma
Relatively little is known about interactions between the airway microbiome and airway host
transcriptome in asthma. Since asthma affects and is affected by the entire airway, studying …
transcriptome in asthma. Since asthma affects and is affected by the entire airway, studying …
Susceptibility to bronchiolitis in infants
AG Vicencio - Current opinion in pediatrics, 2010 - journals.lww.com
RSV remains the most frequently encountered cause of bronchiolitis and contributes to
significant morbidity and mortality worldwide. The investigations highlighted in this review …
significant morbidity and mortality worldwide. The investigations highlighted in this review …
[HTML][HTML] Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers
Background Systemic and local profiles have each been associated with asthma, but
parsing causal relationships between system-wide and airway-specific processes can be …
parsing causal relationships between system-wide and airway-specific processes can be …
Network study of nasal transcriptome profiles reveals master regulator genes of asthma
Background Nasal transcriptomics can provide an accessible window into asthma
pathobiology. Objective Our goal was to move beyond gene signatures of asthma to identify …
pathobiology. Objective Our goal was to move beyond gene signatures of asthma to identify …