The (pro) renin receptor ((P) RR) and soluble (pro) renin receptor (s (P) RR) in pregnancy

SK Morosin, AJ Lochrin, SJ Delforce, ER Lumbers… - Placenta, 2021 - Elsevier
Abstract The (pro) renin receptor ((P) RR) is a multi-functional protein that can be
proteolytically cleaved and released in a soluble form (s (P) RR). Recently, the (P) RR and s …

[PDF][PDF] The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions

IR Bernstein, B Nixon, JM Lyons, KB Damyanova… - Iscience, 2023 - cell.com
In this study we explored the role of hypoxia and the hypoxia-inducible transcription factor
EPAS1 in regulating spermatogonial stem cell (SSC) function in the mouse testis. We have …

Sputum colour can identify patients with neutrophilic inflammation in asthma

K Pabreja, P Gibson, AJ Lochrin… - BMJ Open …, 2017 - bmjopenrespres.bmj.com
Introduction Sputum colour is associated with neutrophilic inflammation in chronic bronchitis
and chronic obstructive pulmonary disease (COPD). Neutrophilia and sputum expectoration …

Osteoblasts are rapidly ablated by virus-induced systemic inflammation following lymphocytic choriomeningitis virus or pneumonia virus of mice infection in mice

S Maltby, AJ Lochrin, B Bartlett, HL Tay… - The Journal of …, 2018 - journals.aai.org
A link between inflammatory disease and bone loss is now recognized. However, limited
data exist on the impact of virus infection on bone loss and regeneration. Bone loss results …