User profiles for "author:Carlos Juan"

Carlos Juan

Immunology associate professor (UIB), Microbiology Researcher Hospital Son Espases …
Verified email at uib.cat
Cited by 7553

The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …

Colonization and diversification: towards a phylogeographic synthesis for the Canary Islands

C Juan, BC Emerson, P Oromı́, GM Hewitt - Trends in Ecology & Evolution, 2000 - cell.com
Abstract Recently, the Canary Islands have become a focus for studies of the colonization
and the diversification of different organisms. Some authors have considered Canarian …

[BOOK][B] Vulnerability: a conceptional and methodological review

V De León, J Carlos - 2006 - collections.unu.edu
Source 4 Page 1 Page 2 UNU Institute for Environment and Human Security (UNU-EHS) UN
Campus Hermann-Ehlers-Str. 10 D - 53113 Bonn, Germany Copyright UNU-EHS 2006 Cover …

[HTML][HTML] β-Lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein

B Moya, A Dötsch, C Juan, J Blázquez… - PLoS …, 2009 - journals.plos.org
It has long been recognized that the modification of penicillin-binding proteins (PBPs) to
reduce their affinity for β-lactams is an important mechanism (target modification) by which …

Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones

G Cabot, AA Ocampo-Sosa… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Recent reports have revealed the existence of widespread extensively drug-resistant (XDR)
P. aeruginosa high-risk clones in health care settings, but there is still scarce information on …

Molecular Mechanisms of β-Lactam Resistance Mediated by AmpC Hyperproduction in Pseudomonas aeruginosa Clinical Strains

C Juan, MD Maciá, O Gutiérrez, C Vidal… - Antimicrobial agents …, 2005 - Am Soc Microbiol
The molecular mechanisms of β-lactam resistance mediated by AmpC hyperproduction in
natural strains of Pseudomonas aeruginosa were investigated in a collection of 10 isogenic …

Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC

G Cabot, S Bruchmann, X Mulet… - Antimicrobial agents …, 2014 - Am Soc Microbiol
We compared the dynamics and mechanisms of resistance development to ceftazidime,
meropenem, ciprofloxacin, and ceftolozane-tazobactam in wild-type (PAO1) and mutator …

Evolution in caves: Darwin's 'wrecks of ancient life'in the molecular era

C Juan, MT Guzik, D Jaume, SJB Cooper - Molecular Ecology, 2010 - Wiley Online Library
Cave animals have historically attracted the attention of evolutionary biologists because of
their bizarre 'regressive'characters and convergent evolution. However, understanding of …

Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem

E Riera, G Cabot, X Mulet… - Journal of …, 2011 - academic.oup.com
Objectives To investigate the mechanisms of carbapenem resistance in the 175
Pseudomonas aeruginosa isolates (39%; 175/448) showing non-susceptibility (European …

Evolution of Pseudomonas aeruginosa antimicrobial resistance and fitness under low and high mutation rates

G Cabot, L Zamorano, B Moyà, C Juan… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Pseudomonas aeruginosa, a major cause of nosocomial and chronic infections, is
considered a paradigm of antimicrobial resistance development. However, the evolutionary …