Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

Pathogen-associated molecular patterns (PAMPs) and endogenous “danger” signals,
known as danger-associated molecular patterns (DAMPs), released from cells alert the …

Alzheimer's disease is characterized by the accumulation of amyloid-beta in plaques,
aggregation of hyperphosphorylated tau in neurofibrillary tangles and neuroinflammation …

The spreading of pathology within and between brain areas is a hallmark of
neurodegenerative disorders. In patients with Alzheimer's disease, deposition of amyloid-β …

We studied the subcellular levels of melatonin in cerebral cortex and liver of rats under
several conditions. The results show that melatonin levels in the cell membrane, cytosol …

Historically neurodegenerative diseases, Alzheimer's disease (AD) in particular, have been
viewed to be primarily caused and driven by neuronal mechanisms. Very recently, due to …

Background Autoimmunity has been reported in patients with severe coronavirus disease
2019 (COVID-19). We investigated whether anti-nuclear/extractable-nuclear antibodies …

The role of melatonin in improving mitochondrial respiratory chain activity and increasing
ATP production in different experimental conditions has been widely reported. To date …

We determined the NF‐κB‐and NOD‐like receptor (NLR) P3‐dependent molecular
mechanisms involved in sepsis and evaluated the role of retinoid‐related orphan receptor …

Duchenne muscular dystrophy (DMD), a lethal disorder characterized by dystrophin
absence, courses with chronic inflammation, sarcolemmal damage, and skeletal muscle …