Rationale: The management of chronic thromboembolic pulmonary hypertension (CTEPH)
has changed over recent years with the growth of pulmonary endarterectomy surgery and …

The earliest structural change in hypoxia-induced pulmonary hypertension is increased
proliferation of adventitial fibroblasts. This fibroproliferative response occurs in acute and …

Hypoxic pulmonary hypertension is a worldwide public health problem. Statins attenuate
hypoxic pulmonary hypertension in animal models, but the mechanism of action and …

Background Outcomes for patients with chronic obstructive pulmonary disease (COPD) with
persistent hypercapnic respiratory failure are improved by long-term home non-invasive …

Introduction Reductions in exacerbation and hospitalisations are the outcomes rated as
most important by people with chronic obstructive pulmonary disease (COPD). Most COPD …

Great progress in the understanding of the pathogenesis of as well as the therapy for
pulmonary hypertension has been made in the last 20 years, but many challenges remain …

Chronic hypoxia, in animals and man, results in remodelling of the pulmonary vasculature
with consequent pulmonary hypertension. The pulmonary artery fibroblast (PAF) has been …

The propulsion control system affects the economics of the HSCT through the mechanisms
indicated. Weight reduction is paramount in an aircraft of this type. Significant reductions are …

The Integrated Propulsion Control System IPCS program was conducted to pursue and
demonstrate the advantages of integrated propulsion controls. The program encompassed …

The feasibility of multivariable design of the entire airplane control system is briefly
addressed. An intermediate step in that direction is to design a control for an inlet engine …