User profiles for "author:Claire Calderwood"

Claire Calderwood

London School of Hygiene & Tropical Medicine
Verified email at lshtm.ac.uk
Cited by 4700

Stillbirths: rates, risk factors, and acceleration towards 2030

JE Lawn, H Blencowe, P Waiswa, A Amouzou… - The Lancet, 2016 - thelancet.com
An estimated 2· 6 million third trimester stillbirths occurred in 2015 (uncertainty range 2· 4–3·
0 million). The number of stillbirths has reduced more slowly than has maternal mortality or …

Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings

RK Gupta, CJ Calderwood, A Yavlinsky, M Krutikov… - Nature medicine, 2020 - nature.com
The risk of tuberculosis (TB) is variable among individuals with latent Mycobacterium
tuberculosis infection (LTBI), but validated estimates of personalized risk are lacking. In …

[HTML][HTML] Dynamics of sputum conversion during effective tuberculosis treatment: A systematic review and meta-analysis

CJ Calderwood, JP Wilson, KL Fielding… - PLoS …, 2021 - journals.plos.org
Background Two weeks' isolation is widely recommended for people commencing treatment
for pulmonary tuberculosis (TB). The evidence that this corresponds to clearance of …

Clinical characteristics and outcomes of adult patients admitted with COVID-19 in East London: a retrospective cohort analysis

D Cheng, C Calderwood… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background Descriptions of clinical characteristics of patients hospitalised withCOVID-19,
their clinical course and short-term inpatient and outpatient outcomes in deprived urban …

[HTML][HTML] The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis

F Conforti, ER Davies, CJ Calderwood, TH Thatcher… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that usually affects elderly
people. It has a poor prognosis and there are limited therapies. Since epigenetic alterations …

[HTML][HTML] Clinical utility of C-reactive protein-based triage for presumptive pulmonary tuberculosis in South African adults

CJ Calderwood, BWP Reeve, T Mann, Z Palmer… - Journal of Infection, 2023 - Elsevier
Background Identification of an accurate, low-cost triage test for pulmonary TB among
people presenting to healthcare facilities is an urgent global research priority. We assessed …

Resolution of blood RNA signatures fails to discriminate sputum culture status after eight weeks of tuberculosis treatment.

C Calderwood, A Sanchez Martinez, J Greenan-Barrett… - MedRxiv, 2023 - medrxiv.org
Background There is concerted effort to reduce the burden of 6 months antimicrobial
treatment for tuberculosis (TB). Early treatment cessation at 8 weeks is effective for most but …

[HTML][HTML] Clinical utility of WHO-recommended screening tools and development and validation of novel clinical prediction models for pulmonary tuberculosis screening …

A Dhana, RK Gupta, Y Hamada… - European …, 2023 - Eur Respiratory Soc
Background: The World Health Organization (WHO) recommends that outpatient people
living with HIV (PLHIV) undergo tuberculosis screening with the WHO four-symptom screen …

[HTML][HTML] Beyond tuberculosis: a person-centred and rights-based approach to screening for household contacts

CJ Calderwood, C Timire, C Mavodza… - The Lancet Global …, 2024 - thelancet.com
Households affected by tuberculosis have syndemic vulnerability, reflecting a concentration
of and interactions between multiple biomedical, psychosocial, and structural determinants …

[HTML][HTML] Evaluation of a comprehensive health check offered to frontline health workers in Zimbabwe

ET Marambire, RMS Chingono… - PLOS global public …, 2024 - journals.plos.org
Health workers are essential for a functioning healthcare system, and their own health is
often not addressed. During the COVID-19 pandemic health workers were at high risk of …