[HTML][HTML] Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis

RK Gupta, CT Turner, C Venturini, H Esmail… - The Lancet …, 2020 - thelancet.com
Background Multiple blood transcriptional signatures have been proposed for identification
of active and incipient tuberculosis. We aimed to compare the performance of systematically …

[HTML][HTML] Genomic investigations of unexplained acute hepatitis in children

S Morfopoulou, S Buddle, OE Torres Montaguth… - Nature, 2023 - nature.com
Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK. Here we report an …

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

PG Hysi, CY Cheng, H Springelkamp, S Macgregor… - Nature …, 2014 - nature.com
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma, and
variability in IOP might herald glaucomatous development or progression. We report the …

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

G Schumann, C Liu, P O'Reilly, H Gao… - Proceedings of the …, 2016 - National Acad Sciences
Excessive alcohol consumption is a major public health problem worldwide. Although
drinking habits are known to be inherited, few genes have been identified that are robustly …

Formulation of lipid core nanocapsules

CG Venturini, E Jäger, CP Oliveira, A Bernardi… - Colloids and Surfaces A …, 2011 - Elsevier
Polymeric nanoparticle aqueous suspensions have been proposed as drug carriers to
improve the efficacy of medicines. Considering those nanocarriers, nanocapsules are …

Sustained release from lipid-core nanocapsules by varying the core viscosity and the particle surface area

E Jäger, CG Venturini, FS Poletto… - Journal of …, 2009 - ingentaconnect.com
Based on the structure of polymeric nanocapsules containing a lipid-dispersed core
composed of caprylic/capric trygliceride (CCT) and sorbitan monostearate (SM), we …

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

H Springelkamp, AI Iglesias, A Mishra… - Human molecular …, 2017 - academic.oup.com
Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …

[HTML][HTML] Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

Q Fan, VJM Verhoeven, R Wojciechowski… - Nature …, 2016 - nature.com
Myopia is the most common human eye disorder and it results from complex genetic and
environmental causes. The rapidly increasing prevalence of myopia poses a major public …

[HTML][HTML] Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

H Springelkamp, R Höhn, A Mishra, PG Hysi… - Nature …, 2014 - nature.com
Glaucoma is characterized by irreversible optic nerve degeneration and is the most frequent
cause of irreversible blindness worldwide. Here, the International Glaucoma Genetics …

Sequence variation of Epstein-Barr virus: viral types, geography, codon usage, and diseases

S Correia, R Bridges, F Wegner, C Venturini… - Journal of …, 2018 - Am Soc Microbiol
One hundred thirty-eight new Epstein-Barr virus (EBV) genome sequences have been
determined. One hundred twenty-five of these and 116 from previous reports were combined …